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Explore the vital functions of proteins, the structure of amino acids, and the characteristics that define them. Discover how proteins play a key role in biological processes, from catalysis to transportation. Learn about zwitterions, the isoelectric point, and the properties that determine amino acids' behavior. Uncover the significance of specific amino acids like phenylalanine, tryptophan, and tyrosine in physiological processes and neurotransmitter regulation. Delve into the world of proteins and amino acids with detailed insights.
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Chapter 14 Amino Acids 14.1-14.4 By: Alexa & Bethany
14.1 What are the many functions of proteins? • Proteins are the most important biological compounds • Functions:-structure for animals, chief constituents of skin, hair, bones, and nails-catalysis: proteins called enzymes are used to help speed up reactions
Functions (cont’d) -movement: muscles are made up of proteins which help us move-transportation: can be used in transportation. for example the protein hemoglobin, in blood, carries oxygen from lungs to cells and carbon dioxide from cells to lungs
functions -hormones: many hormones are made up of proteins such as insulin-protection: if unfamiliar proteins enter the body proteins called antibodies protect you from these foreign intruders. They fight disease and proteins called fibrinogen are used in blood clotting
more functions.. -storage- store materials , similar to the way starch and glycogen store energy-regulation: some proteins control expression of genes and regulate the kinds of proteins made in certain cells • two types of proteins: fibrous proteins and globular proteins
Fibrous Proteins • Insoluble in water • Used for structural purposes
Globular Proteins • More or less soluble in water • Used for non-structural purposes
14.2 What are amino acids? • Organic compounds that contain an amino group and carboxyl group • Proteins are made up of amino acid chains • There are 20 common amino acids, alpha amino acids, in nature are used to make up proteins
14.2(cont’d) • The R group helps us classify amino acids as either non-polar, polar but neutral, acidic, or basic • Non-polar chains repel water(hydrophobic) • Polar but neutral, acidic, and basic all attract water (hydrophilic)
14.3 what are zwitterions? • Compounds that have a positive charge on one atom and a negative charge on another atom • Amino acids are zwitterions -solids with high melting points -soluble in water
14.3 (cont’d) • There is no pH where an amino acid has no ionic character • pH is called the isoelectric point • Every amino acid has a different isoelectric point
14.4 what determines the characteristics of Amino Acids? • The side of the chain is responsible for characteristics of molecules • Amino acids have acidic and basic properties
Properties ex: • -two amino acids, glutamic acid and aspartic acid, have carboxyl groups present in their side chain along with the one already present in amino acids • -because of the carboxylate groups on the side chains of these two amino acids they are negatively charged at a neutral pH
Phenylanine, tryptophan, and tyrosine • Have armotic rings in their side chains • Allow for location and measurement of proteins • Important physiologically, key precursors to neurotransmitters
Phenylanine, tryptophan, and tyrosine • Tryptphan is converted to serotonin (5-hydroxytryptamine) • Low levels of serotonin are associated with depression