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Acetylcholinesterase inhibitors and the risk of hip fracture in Alzheimer’s disease patients: a case-control study. Osteoscoop - Issue N°276 – February 2013. Ach. AchR. Preosteoblasts. AchE. Ach degradation. +. Monocytes. Osteoblasts. Osteoclasts. Osteocytes. Ach. AchR.

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slide1

Acetylcholinesterase inhibitors and the risk of hip fracture in Alzheimer’s disease patients: a case-control study

Osteoscoop - Issue N°276 – February 2013

slide2

Ach

AchR

Preosteoblasts

AchE

Achdegradation

+

Monocytes

Osteoblasts

Osteoclasts

Osteocytes

slide3

Ach

AchR

Preosteoblasts

AchE

Achdegradation

+

Monocytes

Osteoblasts

Osteoclasts

Osteocytes

Alzheimer patients (age >75 years)

TreatedwithAchEinhibitor

(Donepezil; Rivastigmine)

Treatedwithothermolecules

slide4

Ach

AchR

Preosteoblasts

AchE

Achdegradation

+

Monocytes

Osteoblasts

Osteoclasts

Osteocytes

Alzheimer patients (age >75 years)

TreatedwithAchEinhibitor

(Donepezil; Rivastigmine)

Treatedwithothermolecules

1,00

0,49

HIP FRACTURE RISK