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Complex Inheritance. 2-Locus interactions, Epistasis Sept. 18, 2003. Traits were: Clearly distinguishable pairs of phenotypes Traits appeared in all plants Phenotypes distinguished varieties of peas Traits were “stable” in hybrids and subsequent generations. Mendel’s Traits in Peas.

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complex inheritance
Complex Inheritance

2-Locus interactions, Epistasis

Sept. 18, 2003

mendel s traits in peas

Traits were:

  • Clearly distinguishable pairs of phenotypes
  • Traits appeared in all plants
  • Phenotypes distinguished varieties of peas
  • Traits were “stable” in hybrids and subsequent generations
Mendel’s Traits in Peas

2-3

epistasis in biochemical pathways

purple

Epistasis in Biochemical Pathways
  • In Corn, the aleurone pigment is formed by the following pathway.
  • CRAPr
  • pc cl1 cl2 red
  • cc, CIrraapr pr
  • The endosperm color pathway is:
  • Y
  • whiteyellow
  • yy
dihybrid cross complementation
Dihybrid Cross“Complementation”
  • AAcc X aaCC
  • (Yellow) (Yellow)
  • AaCc
  • (Purple)
  • When two mutant strains are crossed and the F1 hybrids show normal function, we say that the two strains complement each other, and the mutant alleles are at different loci so they are non-allelic and the loci are non-homologous.
pleiotropy of y locus function in endosperm

Y

Colorless -carotene Vitamin A

(retinol)

yy

Pig Traits

(grain nutrition)

Endosperm

(color)

(Corn Traits)

Pleiotropy of Y-locusfunction in endosperm
slide8

Corn

Pig

slide10

DNA

chip