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Joint Meeting of the International Collaborative Effort on Injury Statistics (ICE) and the Global Burden of Diseases Inj

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EQ-5D reported outcome after injury: an individual patient data meta-analysis James Black (presenting), Peter Herbison , Ronan Lyons, Suzanne Polinder , Sarah Derrett Injury Prevention Research Unit, University of Otago.

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EQ-5D reported outcome after injury: an individual patient data meta-analysisJames Black (presenting), Peter Herbison, Ronan Lyons, Suzanne Polinder, Sarah DerrettInjury Prevention Research Unit, University of Otago

Joint Meeting of the International Collaborative Effort on Injury Statistics (ICE) and the Global Burden of Diseases Injury Expert Group (GBD-IEG),

Swansea University, 2010

eq 5d and injury outcome
EQ-5D and Injury Outcome
  • Growing influence of patients perspective
    • Growth of Health-Related Quality of Life (HRQoL) measures
    • Lack of information for injury populations
  • An earlier systematic literature search
    • Derrett, Black & Herbison. Journal of Trauma (2009)
    • 44 injury studies included
    • Study heterogeneity prevented pooling published data into a meaningful meta-analysis
eq 5d visual analogue score

Overall self-rated health status

Worst imaginable health state (0)

Best imaginable health state (100)

EQ-5D: Visual Analogue Score
have analysed
Have analysed
  • 21 datasets
    • Ranging from spinal cord injuries to simple strains
  • 10,496 injured person’s EQ-5D injury data
    • 1500+ beyond one year
    • Predictions produced for 25 (of 39) injury categories
the added benefit of ipd meta analysis
The added benefit of IPD meta-analysis

4) A study specific error term

2) Population variance

3) A single studies average

β

1) The population mean quality of life

Adapted with permission from Rabe-Hesketh, Multilevel and Longitudinal Modeling using Stata, Stata Press

future questions
Future questions
  • The burden of injury / Residual impairment –
    • clinical function balanced with subjective functional health status
  • Analytical comparisons of recovery trajectories
    • Cohorts and registries
    • More and more data avalailable

James.Black@lshtm.ac.uk