Division of Health Profession - Know Critical Course Information with SCUHS

1. SOUTHERN CALIFORNIA UNIVERSITY OF HEALTH SCIENCES COLLEGE OF SCIENCE AND INTEGRATIVE HEALTH DIVISION OF HEALTH PROFESSIONS COURSE INFORMATION Course Title: Microbiology Course Number: BIO120M and BIO330 Term: Spring 2016 2nd Block Faculty: M. Reza Mirbolooki, MD, PhD Email: rezamirbolooki@scuhs.edu Phone Number: TBA Office Hours: TBA Time Requirement: (hours/week) Lecture Hours: Laboratory Hours: 37 30 Total Units: 4 CRITICAL COURSE INFORMATION: Lab Instruction • Follow all lab instructions. Special attention to safety is mandatory and essential. • PPE (Personal Protection Equipment)   -UVEX Goggles -Flame resistant Lab Coat/Apron - Nitrile gloves • Students are required to wear long, cotton pants and closed-toed shoes.   • No shorts, heals or flip-flops will be allowed in the laboratory.   • Hair longer than shoulder-length must be pulled back and held with a clip or rubber band. Studying Activities • Be prepared to spend about 20 hours a week outside of school studying and completing homework assignments. • It is important to read about each lecture’s chapter before coming to class. • It would be a good idea to form study groups. COURSE PURPOSE Course Description This course will serve as an introduction to the microbial world. A thorough survey of bacteria, archae, viruses, and microbial eukarya will be offered, citing variety in structure and function. Aspects of biotechnology will be discussed, including recombinant DNA technology and cloning. Microbial growth and genetics will be a focus, as well as an introduction to pathology, epidemiology, immunology, and facets of the immune system response.

2. University Learning Outcomes 1. Evidence-Based Knowledge: The student will utilize foundational health science knowledge; and critically appraise and apply relevant scientific literature in professional healthcare practice. 2. Communication: The student will effectively engage patients/clients, colleagues, and the public using appropriate verbal, non-verbal, and written communication. 3. Professionalism: The student will demonstrate leadership, integrity, respect, and self- reflection while employing ethical and legal standards in professional and community interactions. 4. Integrative Healthcare: The student will serve as an effective member of a healthcare team, collaborating with other professionals to improve community health and patient outcomes for the health of individuals and the community. Course Objectives At the conclusion of this course, a successful student should be able to: 1. Explain the diversity of microbes. 2. Compare various metabolic and replicative processes 3. Classify various microorganisms 4. Apply the principles of microbial genetics 5. Understand the basics of biotechnology equipment and principles, including recombinant DNA methods. 6. Understand pathogenicity and epidemiology. 7. Identify the components of the immune system and describe the process of immune response in detail. INSTRUCTIONAL MATERIALS Optional Text Microbiology: An Introduction to Microbiology, 11/E Tortora, Funke & Case ISBN-10: 0321767381 ; ISBN-13: 9780321767387 Required Text Microbiology: A Laboratory Manual, 1/E Mirbolooki MR
 Provided Materials: Laboratory materials Required Laboratory Attire: No open toe shoes allowed

3. TEACHING METHODS AND ACTIVITIES Format There are 8 hours of lecture and 5 hours of lab each week for 4 weeks. The laboratory will be held on Fridays from 5PM-10PM. The lecture component of this course will be held on Saturdays from 10AM-6PM. The course requires a significant time commitment from students. This commitment is both in terms of reading before lectures and preparing before labs, as well as reviewing the material and doing problems after the lectures and labs. In the four weeks of classes, we will cover the first eighteen chapters of the book. Not every topic will be covered in great depth, but students are expected to study each topic in greater detail through completing the homework and the labs. Homeworks There will be a test given online that will be available on MySCU from Tuesday at 10AM to Saturday at 10AM. There will be 20 questions which come directly from the text book chapters to be covered on the next lecture and questions may come in the form of multiple choice, free response, or fill in the blank. Students will have unlimited time to complete each test. These homeworks need to be completed by students before coming to the lecture on Saturday. Lab. Reports Lab. reports are found in the laboratory manual and are required to be completed during the lab. While students may work in pairs to complete labs, each student must submit his or her own lab. experiment questions. Exams There will be a test given online that will be available on MySCU from Saturday at 6PM to Tuesday at 6PM. There will be 50 questions which come directly from the text book chapters and in-class lectures and questions may come in the form of multiple choice, free response, or fill in the blank. Students will have 75 minutes to complete each test. Final Lab Exam There will be a final lab exam given on the fourth Friday. There will be 15 questions which may come directly from previous lab lectures and lab assignments. Questions may come in a form of multiple choice, free response or fill-in. Students will be given 20 minutes to complete the exam. The students will be given 2 hours for their Lab. practicum. Classroom Expectation Please be professional, prompt, prepared, and polite at all times. The professor will adhere to all polices as found in the BSBS Student Handbook and SCU policy guide. Cellular phones must be kept on silent during class and lab times. Students may not use a phone as a calculator. • • • •

4. As a safety precaution, no food or drinks are allowed inside the lab, but there will be a 30 minute break for eating and drinking outside of the lab. Best Practices for Studying Microbiology Read before and read after each class. Skim the chapter before it is covered in lecture in order to become comfortable with some of the terms associated with each topic. Review each chapter after it is covered in class to enhance your understanding of what was covered in class. Participate during class by taking notes during class and looking over them afterwards. Don't skip class, arrive late, or leave early. Ask questions for clarification when you don’t understand the material. Stay on top of the homework and assignments. Do the assigned problems as close to the time as when the topic is covered in the class to increase the depth of your understanding of specific concepts and will help you learn the material more efficiently and effectively. Do not wait until the night before the homework is due to start the assignment. You will get more out of it if you take the time to really learn the concepts and review the material without being rushed. Find a group of students to study with. Seek out students dedicated to doing well in the course. This makes studying more fun and also helps you learn the material better by teaching what you know and learning from your peers what you don’t know. Explaining these chemistry concepts to others will help you learn the material even better Stay focused by finding an environment where you can study with few distractions. • • • • • • EVALUATION OF STUDENT LEARNING Grading procedures Assessment Points Weight% Lab-Reports (3 @ 50 points each) 150 15 Homework (4 @ 25 points each) 100 10 Exams (4 @ 100 points each) 400 40 Lab Practicum 200 20 Attendance (50 @ 3 points each) 150 15 Total 1,000 100 5th week assignment (BSBS) 100 10

5. Grading scale: Letter Grade Criteria Percentage A Far exceeds the standard for all required work 90-100 B Exceeds the standard for all required work 80-89 C Met the standard for all required work 70-79 D Did not meet the standard for all required work 60-69 F Did not meet the standard for all required work; must retake the course ≤ 59 I Incomplete 0 W Withdrawal 0 Registration Students can add courses by logging in to the MySCU portal. All pre-requisites must be met in order to enroll. Withdrawal Students can withdraw by submitting a formal withdrawal via electronic mail. Disability In keeping with the Americans Disabilities Act of 1990, SCU will accommodate a student’s known physical or mental limitations in order to enable him or her to perform the essential functions of the curriculum, to the extent the necessary accommodations are reasonable and do not impose undue hardship to the University. Interested students should request information regarding the services offered by the University. The Learning Resource Specialists are located in the library and can assist with the documentation required to access special services due to disabilities. Student Policy Manual The Policy Manual can be easily accessed by: (1) going on to the University Homepage at: http://www.scuhs.edu/ (2) Then opening the link for MY SCU (3) Logging on using your university supplied login and password (4) Next, opening the header for “Department” (5) Next opening the header for “Human Resources” (6) Finally, opening the header for the “Policy Manual.”

6. Academic Dishonesty Students are expected to adhere to the highest standards of academic honesty. In this class, cheating will not be tolerated. Plagiarism includes passing someone else’s ideas off as your own without citing proper credit. Cheating includes looking at another student's test during an exam, allowing other students to copy your work, use of unauthorized materials during an exam, presenting lab reports that are not your original work, and recording laboratory data that was not actually observed. These are all prohibited in this program. Collaboration and discussion are encouraged, but it is important for each student to individually complete each assignment. Any student who is academically dishonest material will receive a failing grade. University Policies Students are expected to spend at least two hours for each lecture or practicum hour and one hour for every two laboratory hours of course time per week in activities and assessments outside the classroom. Examples of activities include, but are not limited to: writing papers; reading articles or text; small group work; presentations; completing assignments; preparation for assessments; online activities and other activities that do not include direct instructor interaction and involvement. All university policies apply to this course and all others. For full policy information please consult the university SCU Policy Manual. For a quick reference guide to the following policies: make-up examination, F-challenge examination, grade posting, results of failing grades, student support information, syllabus amendments, special needs, student conduct, and attendance, please consult the academic policies document housed on the Online Student Services [the preceding is a hyperlink] Microbiology Program Learning Outcomes: Learning Objective Outcome The course will begin with a survey of the types of microbes. Biotechnology, as well as microbial growth and genetics will also be a focus. Students will conduct experiments in lab and submit pre-lab and post-lab assignments describing the biological relevance of laboratory activities. Basic Science Knowledge This class introduces students to more technical procedures through laboratory assessments as well as theoretical knowledge that can be utilized in future testing of claims and assessing accuracy of other people’s assertions. Scientific Reasoning Textbook reading is assigned and students are required to do many hours of independent learning. By asking questions on readings and outside learning, to professors and peers, students will gain more knowledge on how to find and assimilate important information from sources. Information Literacy

7. Through the utilization of in class discussions, lab reports, online discussion board posts and responses, students will learn how to share ideas and give constructive criticisms. Peer and professor critiques will help students grow to become more effective collaborators and communicators. Communication Effectiveness The portfolio project ties together basic aspects of microbiology in relation to specific integrative health areas. This project helps students grow in understanding of integrative health in general while seeing applications of the specific biology coursework they are working on. Integrative Health Knowledge Microbiology I General Education Outcomes: General Education Objective Outcome Lab assignments as well as online discussion board posts and responses focus on effective written communication. English & Writing Composition Various physiological systems will be analyzed. Students will conduct interactive activities in lab and submit pre-lab and post-lab assignments describing the structure and function of various physiological systems. Science & Mathematics Online discussion board posts and responses as well as online submission, online videos, self-check quizzes, and online tests are accessed using the online platform for SCU, e-Racer. All homework will be written through platforms such as Microsoft Word. Computer Language Historical topics on anatomy and physiology in general are introduced and examined through online discussions. The time, significance for the time, and ways discoveries came about are analyzed. Also, the reactions people of the time had and some the cultural relevance and implications of the discoveries. History and Social Science/ Social Behavior

8. 2016 COURSE SCHEDULE Week Chapter s Date Description Orientation: Laboratory Guidelines 19- Feb Laboratory: Microscopy and Simple Staining Lab Report 1 Assignment Due Homework 1 Assignment Due Lecture 1: Characteristics and definitions of microbes, bacteria, archaea, algae, fungi, protozoa, viruses Lecture 2: Introduction to microbial classification. Lunch Break Lecture 3: Bacterial structural components: bacillus, coccus, spiral, glycocalyx, capsule, flagella, fimbriae, pili, cell wall, membranes. Chemotaxis and phototaxis. Lecture 4: Thermophiles, acidophiles, halophiles, biofilms. Bacterial growth: lag phase, log phase, stationary phase, death phase, control methods including disinfectants and antibiotics. Exam 1 due 02-24-16 Chapters 1-4, (Optiona l Review: Ch. 2, 5) 1 20- Feb Laboratory: Differential Staining Lab Report 2 Assignment Due 26- Feb Homework 2 Assignment Due Lecture 1: Bacterial DNA structure. Chromosomes, plasmids, supercoiling, genes, replication, transcription, translation, regulation of gene expression, repression, induction. Lecture 2: Missense mutation, nonsense mutation, frameshift mutation. Lunch Break Lecture 3:Alkylating agents, intercalators, radiation, Photolyases, BES. Lecture 4:Vertical and horizontal gene transfer. Transduction, transformation, conjugation. Recombinant DNA technology, GMO’s, cloning, PCR, genomic libraries, colony hybridization, gene therapy.
 Exam 2 due 03-02-16 6-9 2 27- Feb 04- Mar Laboratory: Culturing, Subculturing, and differential culturing Lab Report 3 Assignment Due

9. Homework 3 Assignment Due Lecture 1: Three-domain system, cell lineage, taxa, identification methods. Bacteria: protobacteria, actinobacteria, various other phyla. Lecture 2: Survey of archaea, fungi, algae, protozoa. Lunch Break Lecture 3: Viral structure, capsid, protein coat, relative sizes. Lecture 4: Lytic cycle, lysogenic cycle, viroids, prions, oncogenes. Exam 3 due 03-09-16 10-13 3 05- Mar 11- Mar Laboratory: Examine Cultures From Previous week Final Lab Exam Homework 4 Assignment Due Lecture 1: Pathology: etiology, pathogenesis, infection, disease, Koch’s postulates, communicable vs. contagious disease. Lecture 2: Epidemiology: descriptive vs. analytical, exotoxins, endotoxins. Lunch Break Lecture 3: The immune system: innate immunity vs. adaptive immunity, formed elements in blood, lymphatic system, phagocytosis, inflammation, antigens and antibodies, vaccines, allergy, autoimmune disease, immunodeficiency. Exam 4 due 03-16-16 4 12- Mar 14-18 Personal Reading Assignment The students at BSBS program must study chapters 21-26 and take an online exam. The deadline to take the sam is March 19th 2016 at 11:55 PM. 19- Mar 5 21-26 Syllabus prepared by: M. Reza Mirbolooki Date:Feb 15, 2016