Patrick An Introduction to Medicinal Chemistry 3/e Chapter 9 DRUG DISCOVERY: FINDING A LEAD

Patrick An Introduction to Medicinal Chemistry 3/e Chapter 9 DRUG DISCOVERY: FINDING A LEAD Part 3: Section 9.4 (Lead compounds from the synthetic world)

Contents Part 3: Section 9.4 - Lead compounds from the synthetic world 4.4. Lead Compounds from the Synthetic World - Organic Synthesis - Combinatorial Synthesis - Combinatorial Synthesis - Peptide Synthesis - Combinatorial Synthesis - Heterocyclic Synthesis (5 Slides) [14 slides]

SYNTHETIC COMPOUNDS 4.4 Lead Compounds from the Synthetic World SYNTHETIC COMPOUNDS

4.4 Lead Compounds from the Synthetic World PRONTOSIL

4.4 Lead Compounds from the Synthetic World SULFANILAMIDE

4.4 Lead Compounds from the Synthetic World TNT

4.4 Lead Compounds from the Synthetic World RUBBER INDUSTRY ANTABUSE

4.4 Lead Compounds from the Synthetic World ORGANIC SYNTHESIS

4.4 Lead Compounds from the Synthetic World COMBINATORIAL SYNTHESIS AUTOMATED SYNTHETIC MACHINES

AMINO ACID RESIN BEAD AMINO ACIDS X PEPTIDE 4.4 Lead Compounds from the Synthetic World COMBINATORIAL SYNTHESIS - PEPTIDE SYNTHESIS

Y CHR1R2 4.4 Lead Compounds from the Synthetic World COMBINATORIAL SYNTHESIS - HETEROCYCLIC SYNTHESIS RESIN BEAD N N O

R2 R3 H RESIN BEAD 4.4 Lead Compounds from the Synthetic World COMBINATORIAL SYNTHESIS - HETEROCYCLIC SYNTHESIS N N O

R2 R3 R4 R5 RESIN BEAD 4.4 Lead Compounds from the Synthetic World COMBINATORIAL SYNTHESIS - HETEROCYCLIC SYNTHESIS N N O EtO O

R2 R3 R4 R5 RESIN BEAD 4.4 Lead Compounds from the Synthetic World COMBINATORIAL SYNTHESIS - HETEROCYCLIC SYNTHESIS N N N HN O

Y R2 R3 R4 R5 4.4 Lead Compounds from the Synthetic World COMBINATORIAL SYNTHESIS - HETEROCYCLIC SYNTHESIS RESIN BEAD N N N HN O

Patrick An Introduction to Medicinal Chemistry 3/e Chapter 9 DRUG DISCOVERY: FINDING A LEAD