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The Closure Procedure. The VNUS Closure Procedure is a minimally invasive treatment alternative to vein stripping. Approximately 25 million Americans suffer from venous reflux. . What is Venous Reflux Disease?. Progressive condition caused by poor return of blood from the legs to the heart

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The Closure Procedure

  • The VNUS Closure Procedure is a minimally invasive treatment alternative to vein stripping.

  • Approximately 25 million Americans suffer from venous reflux.


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What is Venous Reflux Disease?

  • Progressive condition caused by poor return of blood from the legs to the heart

  • Symptoms include:

    • Pain

    • Varicose veins

    • Leg heaviness & fatigue

    • Swollen limbs

    • Skin changes and skin ulcers

  • Risk factors

    • Multiple pregnancies

    • Family history

    • Obesity

    • Standing profession


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How Venous Reflux Occurs

  • Vein valves fail

  • Reflux and poor drainage of venous blood result

  • Column of blood causes pressure to build up in leg veins

  • Increased pressure may cause surface veins to become varicose

Dilated Vein

Normal Vein

Heart

Foot

Valve Open

Valve Closed

Leaky Valve


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The VNUS Closure® Solution

A Minimally invasive alternative to vein stripping surgery

Disposable catheter

inserted into vein

Vein warmed and collapses

Catheter slowly withdrawn, closing vein


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Highlights of the Closure Procedure

  • Relief of symptoms

  • Short recovery

  • Resume normal activities within 1-2 days

  • Same day procedure

  • Local or regional anesthesia

  • Good cosmetic outcome with minimal to no scars


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The Closure Procedure – A treatment that works

1

Symptoms Pretreatment 6 weeks 2 Years

Leg Pain 85% 6% 5%

Leg Fatigue 85% 12% 5%

Edema (swelling) 19% 8% 0%

Prior to the Closure procedure, 85% of patients reported leg pain. After the Closure procedure, 94% of patients at 6-weeks and 95% of patients at 2-years, did not report residual leg pain.

1Weiss RA, et al: Controlled Radiofrequency Endovenous Occlusion Using a Unique Radiofrequency Catheter Under Duplex Guidance to Eliminate Saphenous Varicose Vein Reflux: A 2-Year Follow-Up. Dermatol Surg 2002; 28:38-42.


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The Closure Procedure With No Adjunctive Phlebectomy*

Courtesy of Robert Merchant, MD

Pre-Tx – Lt. Leg

2 Weeks Post Closure-Lt. Leg

*Individual results may vary


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Patient Satisfaction

98% of patients who have undergone the Closure procedure are willing to recommend it to a friend or family member.

Courtesy of Dr. Robert Merchant, MD

Courtesy of Robert Merchant, MD

Pre-Treatment

2 Weeks Post-Closure

*Individual results may vary


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Safety Summary

Indication:

The Closure System is intended for endovascular coagulation of blood vessels in patients with superficial venous reflux.

Contraindications:

Patients with a thrombus in the vein segment to be treated.

Potential Risks & Complications:

Potential complications include, but are not limited to the following: vessel perforation, thrombosis, pulmonary embolism, phlebitis, hematoma, infection, paresthesia, skin burns.


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