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بسم الله الرحمن الرحیم

بسم الله الرحمن الرحیم. Dental problems in leukemia children. 2th leading cause in children Hematopoietic malignancy proliferation abnormal leukocyte Blast cell. Classification of leukemia on morphology. ALL Erythrolukemia

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بسم الله الرحمن الرحیم

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  1. بسم الله الرحمن الرحیم

  2. Dental problems in leukemia children • 2th leading cause in children • Hematopoietic malignancy • proliferation abnormal leukocyte • Blast cell

  3. Classification of leukemia on morphology • ALL Erythrolukemia • ANL Megakaryocytic leukemia • AML • AML CML • AMML CLL • APL

  4. Type onset, prognosis leukemia

  5. Major Agents & side effect in leukemia

  6. Oral Manifestations of leukemia • Oral sign and symptoms (75% Adult , 29% children) • Regional lymphadenopathy • Mucus petechiae , Ecchymosis • Gingival bleeding , Hypertrophy , Pallor , Ulceration

  7. Oral Manifestation of leukemia • Cranial nerve palsies • Chin & Lip Paresthesis • Odontalgia

  8. (…Continue) • Jaw pain , loss teeth , Extruded teeth • Gangrene stomatitis • Stasis in vascular channels • Anoxia

  9. Other manifestation in leukemia • Skeletal lesion • Osteoprosis • Enlarge haversian & Volkmann canal • Osteolytic lesion • Loss of trabeculation

  10. Dental Healthcare protocol in leukemia • Primary Medical Diagnosis • Anticipated clinical course and prognosis • Present & Future therapeutic modalities • General health status • Present hematologic status

  11. Platelet count in leukemia

  12. White Blood cell count in leukemia

  13. Formula for ANC ANC = (% Neutrophils + bond ) × total WBC ÷ 100

  14. Topical obtundents for oral pain in leukemia

  15. Bone Marrow , stem cell Transplant • Aplastic Anemia • Thalacemia • Severe Immunodeficiency • Leukemia • Total body Irradiation • HLA Compatible • GVHD • Risk infections

  16. Oral complications of BMT • ulceration , Mucosit • Transient salivary gland dysfunction • Oral bleeding  platelet transfusion or amicar , Avitene

  17. Pre transplantation preparation • Four week before BMT • Consultation with oncologist • Admission and Nursing interventions • Remission phase • Solid tumors

  18. The end Dr . Jabbarifar 2007

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