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بسم الله الرحمن الرحیم

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بسم الله الرحمن الرحیم. Dental problems in leukemia children. 2th leading cause in children Hematopoietic malignancy proliferation abnormal leukocyte Blast cell. Classification of leukemia on morphology. ALL Erythrolukemia

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بسم الله الرحمن الرحیم

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  1. بسم الله الرحمن الرحیم

  2. Dental problems in leukemia children • 2th leading cause in children • Hematopoietic malignancy • proliferation abnormal leukocyte • Blast cell

  3. Classification of leukemia on morphology • ALL Erythrolukemia • ANL Megakaryocytic leukemia • AML • AML CML • AMML CLL • APL

  4. Type onset, prognosis leukemia

  5. Major Agents & side effect in leukemia

  6. Oral Manifestations of leukemia • Oral sign and symptoms (75% Adult , 29% children) • Regional lymphadenopathy • Mucus petechiae , Ecchymosis • Gingival bleeding , Hypertrophy , Pallor , Ulceration

  7. Oral Manifestation of leukemia • Cranial nerve palsies • Chin & Lip Paresthesis • Odontalgia

  8. (…Continue) • Jaw pain , loss teeth , Extruded teeth • Gangrene stomatitis • Stasis in vascular channels • Anoxia

  9. Other manifestation in leukemia • Skeletal lesion • Osteoprosis • Enlarge haversian & Volkmann canal • Osteolytic lesion • Loss of trabeculation

  10. Dental Healthcare protocol in leukemia • Primary Medical Diagnosis • Anticipated clinical course and prognosis • Present & Future therapeutic modalities • General health status • Present hematologic status

  11. Platelet count in leukemia

  12. White Blood cell count in leukemia

  13. Formula for ANC ANC = (% Neutrophils + bond ) × total WBC ÷ 100

  14. Topical obtundents for oral pain in leukemia

  15. Bone Marrow , stem cell Transplant • Aplastic Anemia • Thalacemia • Severe Immunodeficiency • Leukemia • Total body Irradiation • HLA Compatible • GVHD • Risk infections

  16. Oral complications of BMT • ulceration , Mucosit • Transient salivary gland dysfunction • Oral bleeding  platelet transfusion or amicar , Avitene

  17. Pre transplantation preparation • Four week before BMT • Consultation with oncologist • Admission and Nursing interventions • Remission phase • Solid tumors

  18. The end Dr . Jabbarifar 2007

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