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Analysis of MUC16 and Caveolin1 Interactions in SKOV3 and OVCAR3 Cell Lines

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This study investigates the interaction between MUC16 and Caveolin1 in various ovarian cancer cell lines, including SKOV3, SKOV3-CTD, and NIH:OVCAR3. We utilized a panel of control scFv constructs to assess their effects on apoptosis-related proteins like Bcl-2, Bcl-XL, Bax, FADD, and XIAP. The results, represented in figures and merged images, shed light on the signaling pathways influenced by MUC16 and Caveolin1 in cancer progression and treatment resistance.

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Analysis of MUC16 and Caveolin1 Interactions in SKOV3 and OVCAR3 Cell Lines

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  1. Figure S1 MUC16 Caveolin1 Merge

  2. A Figure S2 * B C CTRL scFv 1:9#7 scFv 1:9#9 scFv 1 2 3 4 0 8 1 2 3 4 8 1 2 3 4 8 0 0 Bid Tubulin E SKOV3-CTD D NIH:OVCAR3 SKOV3-EV Ctrl scFv SKOV3 1:9#9 1:9#7 Bcl-XL Bcl-XL Bcl-2 Bcl-2 Bax Bax FADD FADD XIAP XIAP tubulin tubulin

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