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caFE Server

caFE Server. Siteman Cancer Center. Introduction. Annotate probes on microarrays using publicly available biomedical databases Automatically update annotations on a regular basis Web-based and API based query search Uses caCORE SDK (version 1.0.3) generated code

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caFE Server

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  1. caFE Server Siteman Cancer Center

  2. Introduction • Annotate probes on microarrays using publicly available biomedical databases • Automatically update annotations on a regular basis • Web-based and API based query search • Uses caCORE SDK (version 1.0.3) generated code • Working towards caGRID compliance

  3. Data Sources • Entrez Gene • UniGene • Gene Ontology • dbSNP • UniSTS • HomoloGene • PubMed

  4. Annotation Interlinks Microarrays caArray Custom Entrez Gene UniGene GenBank Gene ID UniGene ClusterID Accession Number HomoloGene dbSNP PubMed Gene Ontology Orthologus genes RefSNP ID Pubmed relationship GO terms

  5. Limitations • Initial run of PubMed data curation takes 2-3 months • APIs generated using caCORE SDK • Not optimized for complex searches • Performing searches that involves complex computations. • For example, searching for literature correlation with depth 2 or more • Meta-information of caArray is not stored

  6. Demo

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