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Cystic Fibrosis Infertility in Men and Women. Mary Goodman March 15, 2006. Infertility in Males. Although men with Cystic Fibrosis still may have a great sex life, the majority of them are infertile.

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Presentation Transcript
infertility in males
Infertility in Males
  • Although men with Cystic Fibrosis still may have a great sex life, the majority of them are infertile.
  • 99% of adult males with Cystic Fibrosis are characterized by congenital bilateral absence of vas deferens (CBAVD).
cbvad
CBVAD
  • Congenital bilateral absence of the vas deferens
  • The improper development of the tube through which sperm are released from the testes.
  • Similar to being born with a vasectomy; you have sperm but pathway to release them is missing.
  • Causes of CBVAD are genetic mutations and variations in the CF gene.
female infertility
Female Infertility
  • Females with CF are less fertile than normal healthy women.
  • Delayed puberty and amenorrhoea are common due to malnutrition.
  • Women with CF have a thicker cervical mucus which makes it hard for the sperm to swim through, however not impossible.
resources
Resources
  • Jarzabek K, Zbucka M, Pepinski W, Szamatowicx J, Domitrz J, Janica J, Wolczynoski S, Szamatoqicz M. 2004. Cystic Fibrosis as a cause of infertility. Reproductive Biology. Vol. 4, No. 2.
  • www.cysticfibrosismedicine.com
  • www.healingwell.com/library/cysticfibrosis/info1.asp
  • www.dnadirect.com/resource/conditions/cystic_fibrosis/faqs_CF_infertility.jsp