What are we doing? In this activity you and your group will play the role of a 2 parents. You will work in groups of six. 3 students will play the mother 3 students will play the father
You will receive a baggie with pipe cleaners and beads. The pipe cleaners represent chromosomes and the beads represent genes located on the chromosomes. In humans, there are 23 pairs of chromosomes and thousands of genes, but for this exercise, we will only focus on a few.
you must answer each of
1- What is the Mother’s genotype?
2- What is the Mother’s phenotype?
3- What is the Father’s genotype?
4- What is the Father’s phenotype?
5- What is the offspring's possible genotype?
6- What is the offspring’s possible phenotype?
7- For the hemophilia: Is Mom a carrier?
8- Why doesn’t Dad get an allele for this trait?
Hemophilia is carried on the X chromosome. It is called an X linked genetic disorder. A women who is a carrier for hemophilia has the genetic mutation on one of her X chromosomes . She will have another non mutated X chromosome that will usually somewhat compensate for the defect in the other. It is not uncommon for women who carry the hemophilia gene to have low levels of clotting factor and have bleeding problems. A man who has hemophilia has the genetic mutation on his only X chromosome. He does not have another X chromosome to compensate for the defect so he will have hemophilia.
--The “dad” places one set of the homologous pairs (ex: that longer set) behind his back, with a chromosome in each hand. The “mom” picks the hand she wants for the child. Lay this chromosome on the table in front of you and set the other aside.
-- Repeat this procedure for the other homologous pair (ex: shorter set) and for the sex chromosomes. Its should be noted that if the blue chromosome gets chosen from the sex chromosomes, the child in this cross is going to be a boy.
--Now the “mom” places one set of the homologous pairs behind her back and the male chooses.
-- The chromosomes chosen and set on the table in front of you are the genes your first child received.
Arrange the chromosomes into homologous pairs and figure out what phenotypes (appearance or trait) the offspring has.
To get the percents, divide the number you have by the total number and x 100.
Girls ______% Boys ______%
Brown eyes ______%
Blue eyes ______%
Dark hair ______%
Blonde hair ______%
Hemophiliac boys ______%
Hemophilac girls ______%