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Learn about essential nutrients, protein deficiency, malnutrition diseases like Kwashiorkor, potential solutions, genetic diseases like PKU, fatty acids types, and their impact on health. Discover the importance of balanced diets and the role of fatty acids in cardiovascular health.
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Nutrients • Chemical substance found in foods and used in the human body • Absorbed to give you energy, strengthen bones, prevent you from getting a disease (vitamins) • Some amino acids and lipids can be synthesized by the body, many cannot • So, we get these from foods
Essential Nutrients • Nutrients obtained from foods because your body cannot synthesize them • Examples: • Essential amino acids • Essential fatty acids • Minerals • Most vitamins • Water • Carbohydrates are not essential nutrients b/c it is possible to live on diets with little to no carbohydrates • Not highly advised …
Amino Acids • 20 amino acids proteins • Nine of these amino acids cannot be synthesized in the body • The human genome lacks the DNA sequence • Referred to as essential amino acids • The other 11 can be manufactured in the body; called nonessential amino acids
Protein Deficiency • Deficiency • A person is not getting enough of a certain nutrient • This causes a health problem • Protein deficiency • Can lead to insufficient production of blood plasma proteins • Retention of fluids in certain tissues • Notably the walls of the intestine • Example of malnutrition
Malnutrition • Imbalance in the diet which leads to one or more diseases • Typically caused by a deficiency; in some circumstances, caused by an excess of one or more essential nutrients • Example: Kwashiorkor Disease • Common in children in non-industrialized countries • Name comes from Ghana • A second born child receives milk from his mother, but leaves little to no milk for the first born • First born may develop Kwashiorkor (protein deficiency)
Kwashiorkor • Symptoms include: • Fatigue, growth failure, loss of muscle mass edema, decreased immunity • Complications: • Coma, shock, permanent mental and physical disability
A Simple Cure … ? • Eat more protein • However, sources of protein are expensive • Not an easy option for many families • Humanitarian efforts • High protein biscuits • Teach people how to raise chicken • Introduce eggs into diets
Turn and Talk • To what degree do you think the following are factors in malnutrition? • Poverty and wealth • Cultural differences concerning dietary preference • Climatic conditions • Poor distribution of food (i.e. insufficient roads, bridges, railways) • A nomadic lifestyle • Corrupt politicians misusing agriculture or aid money • Lack of health care leading to a cycle of disease and poverty
PKU • Genetic disease caused by a mutated gene • The gene codes for a specific enzyme which converts the amino acid phenylalanine to tyrosine • People with PKU cannot convert phenylalanine into tyrosine, so they have very high levels of phenylalanine • This affects brain development • Untreated PKU severe mental problems and learning difficulties
Solution • PKU can be diagnosed early with a blood test at birth • Parents can be informed what treatment if necessary • Common to follow a diet low in protein to avoid phenylalanine (eliminate milk, peanuts, cheese, meat) • Aspartame contains phenylalanine (one reason to label all food products)
Fatty Acids • Not all fats are created equal • What is the same: • Carboxyl group (COOH) • Methyl group (CH3) • Hydrocarbon tail (in the middle) • See figures on pages 210-211 • 7.1, 7.2, 7.3
Saturated Fatty Acids • Saturated with hydrogen atoms • No double bonds between the carbon groups • The shape is straight – no kinks • Animal products: • Bacon, butter, fat in red meat • Generally solid at room temperature • Eat in extreme moderation …
Monounsaturated Fatty Acids • If one double bond exists in the chain of hydrocarbons, the fatty acid is NOT saturated • Monounsaturated fatty acids • Two or more double bonds … • Polyunsaturated fatty acids • Typically comes from plants • Olives, avocados, nuts • Tend to be liquid at room temperature
Cis vs. Trans fatty acids • In some processed foods (snacks, cake), polyunsaturated fats are hydrogenated • This means the double bonds are eliminated by adding hydrogen atoms • Straightens out the natural bent shape • Naturally curved fatty acids are called cis • The hydrogenated fatty acids are called trans • AVOID TRANS FATS!!
Omega 3 Fatty Acids • Example of cis fatty acids • Healthy • Good for your brain and heart • Salmon, sardines, mackerel (fish)
Diets rich in fats • The shape is important • Fatty acids that are curved are more easily picked up in the current of the blood stream • Straight fatty acids can lie flat against the walls • Deposits combine with cholesterol to form plaque • Inner lining of blood vessels
Plaque • Reduces blood flow • A chunk may break off, get lodged, so no blood can pass through • If this happens in the heart (heart attack) • If this happens in the brain (stroke)
So, about eating fats • A diet rich in saturated fats has a much higher chance of leading to serious cardiovascular problems later in life • Diets rich in polyunsaturated fats lead to lower quantities of plaque • Also tend to carry cholesterol away • Both types have high amounts of energy (CALORIES), so consuming a lot of either type is unhealthy
So, take away message • When you eat, look at the food labels • Look for cholesterol, saturated fatty acids, polyunsaturated acids, and trans fat • Your body needs healthy fat to function, but focus on eating a balanced diet • Cardiovascular disease is also influenced by genetics, amount of exercise, and smoking
Vitamins and minerals • Often grouped together, but structurally very different • Minerals are inorganic • Does not contain carbon • Not synthesized by organisms • Rocks, soil, or sea water • Vitamins are organic • Synthesized in plants and animals • Contain carbon
Examples • Minerals: • Sodium, calcium, iron • Vitamins: • Vitamin A, C, D, ... • Both are needed in very small amounts (we’re talking milligrams) • Both prevent dificiency diseases
Vitamin C • Recommended level 30-60 mg per day • Check your food labels • Vitamin C protects against infection, wound healing, and maintaining healthy gums, teeth, bones and blood vessels • Excess vitamin C can lead to kidney stones • Too little vitamin C can cause scurvy • Fluid retention, loss of teeth, bleeding into joints, and anemia • Untreated may be fatal
Vitamin D • Formation of bones • Insufficient supply of vitamin D may cause rickets. • Deformities in the bones • Children with rickets do not reach optimal height; legs are often bowed inward or outward at the knees (see picture on page 216)
Vitamin D • Sources: • Exposure to sunlight • Food (fish: salmon, tuna, sardines; eggs, liver, milk and cereal are often fortified) • Vitamin supplements • Risks? • Exposure to sun UV radiation (may cause sunburn and skin cancer called malignant melanoma)
Dietary Supplements • May be taken if the foods you eat do not provide you with vital minerals and nutrients
Iodine • Iodine is a component of thyroxin, a hormone made by the thyroid gland • Regulates growth • Too little iodine inflammation of the thyroid gland • This is called a goiter • Babies may suffer from growth and mental retardation
Why don’t we see a lot of goiters in industrialized countries? • Iodine is added to salt • US; 1924 • By the 1950s, goiters were essentially nonexistent in the US
Fiber • “Roughage” – provides bulk • Cellulose in plant material • Reduces likelihood of constipation and chances of intestinal problems like colon cancer • Also links to reduced cardiovascular disease • Toxins bind to fiber and carried out of the body • Links to managing body mass fiber helps you feel fuller longer • Many people do not get the amount of fiber they need on a daily basis.
Take away message • So what are some of the foods you should be eating? Why? • What are foods you should avoid, or eat in moderation? Why?