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Correlation of Salivary Mucin Mg2 and the Prevalence of Baby Bottle Tooth Decay

Correlation of Salivary Mucin Mg2 and the Prevalence of Baby Bottle Tooth Decay. Mochamad Fahlevi Rizal Endang W Bachtiar Boy M Bachtiar Heriandi Sutadi. Introduction. Caries Prevalence in Indonesia Baby bottle tooth decay Caries Detection for Children

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Correlation of Salivary Mucin Mg2 and the Prevalence of Baby Bottle Tooth Decay

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  1. Correlation of Salivary Mucin Mg2 and the Prevalence of Baby Bottle Tooth Decay MochamadFahlevi Rizal Endang W Bachtiar Boy M Bachtiar HeriandiSutadi

  2. Introduction • Caries Prevalence in Indonesia • Baby bottle tooth decay • Caries Detection for Children • Mucin MG2 responsible to Streptococcus mutansadhesion

  3. Mucin MG2 and Streptococcus mutans • Salivary mucin MG2 • α-enolaseStreptococcus mutans

  4. Salivary Protein

  5. Mucin MG2 • Single monomeric protein • Molecular weigth are less then mucin MG1 • Sintesized in acinar serous cell and detected in all sero mucous salivary glands • Adhere with much oral bacteria such as Streptococcus mutans

  6. Methods • Consecutive Sampling • Inclusion criteria: children between 3 – 5 yo who have dringking milk by bottle history • Unstimulate saliva collecting • ELISA method with anti mucin MG2 antibody in 450 nm

  7. Result

  8. Salivary MucinMG2 .5 .4 .3 .2 .1 0.0 Observed -.1 Cubic -2 0 2 4 6 8 10 12 14 16 deft

  9. Discussion • Caries prevalence was represented by deft • Incresingmucin MG2 concentration will increase caries insidence

  10. Discussion • Mucin MG2 will used to: - caries prediction - caries prevention

  11. Conclussion Mucin MG2 correlate to caries prevance in baby bottle tooth decay and could be a caries predictor and a tool to prevent caries molecularly

  12. Acknowledgement Part of this research was supported by RisbinIptekdok Grant Research 2007 from Department of Health Republic of Indonesia

  13. Thank You

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