General Pharmacology. 205b. Neuromuscular Blocking Agents (NMBAs). Cause skeletal muscle weakness or paralysis for purpose of preventing movement. Neuromuscular Blocking Agents (NMBAs). Cause skeletal muscle weakness or paralysis for purpose of preventing movement Two types
Generic name Proprietary name
- Short acting paralytic ideal for intubation or similar procedures
Methadone is mainly used in the treatment of opioid dependence. It has cross-tolerance with other opioids including heroin and morphine, offering very similar effects and a longer duration of effect. Oral doses of methadone can stabilise patients by mitigating opioid withdrawal syndrome. Higher doses of methadone can block the euphoric effects of heroin, morphine, and similar drugs. As a result, properly dosed methadone patients can reduce or stop altogether their use of these substances.
barbiturate and the most widely used anticonvulsant worldwide, and the oldest still commonly used