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PROGNOSIS

PROGNOSIS. CLINICAL QUESTON: What is the long term prognosis of rheumatic fever patients receiving regular benzathine penicillin? Population: Rheumatic fever patients Intervention: Prophylaxis with benzathine penicillin

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PROGNOSIS

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  1. PROGNOSIS

  2. CLINICAL QUESTON: What is the long term prognosis of rheumatic fever patients receiving regular benzathine penicillin? Population: Rheumatic fever patients Intervention: Prophylaxis with benzathine penicillin Outcome:Valvular heart disease, Recurrence of rheumatic fever Bacterial endocarditis, Death Methods: Cohort SEARCH TERMS: Rheumatic fever , prophylaxis, long term prognosis

  3. Long-Term Prognosis of Rheumatic Fever Patients Receiving Regular Intramuscular Benzathine Penicillin. Tompkins D, Boxerbaum B, Liebman J., Circulation Journal of the American Heart Association 45;543-551, 1972

  4. Critical Appraisal

  5. Critical Appraisal

  6. How large is the likelihood of outcome to occur in those with the prognostic factor in a specified period of time? Was it statistically significant?

  7. Can the results help me in caring for my patients?

  8. Resolution of the problem in the scenario Based on the Thompson et al. study, our group advices that the patient in the case scenario continue with her intake of benzathine penicillin monthly even if she had an incident on rheumatic fever while taking it because further valvular damage, bacterial endocarditis, higher risk for recurrence of rheumatic fever and even death would occur without it.

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