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Centrifugal Pump for Neuroendoscopy. Client: Joshua E. Medow, MD, Department of Neurological Surgery Advisor: William L. Murphy, PhD Team: Jenna Spaeth, Team Leader Kellen Sheedy, Communicator Laura Piechura, BWIG Holly Liske, BSAC. Neuroendoscopy.

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centrifugal pump for neuroendoscopy

Centrifugal Pump for Neuroendoscopy

Client: Joshua E. Medow, MD, Department of Neurological Surgery

Advisor: William L. Murphy, PhD

Team: Jenna Spaeth, Team Leader

Kellen Sheedy, Communicator

Laura Piechura, BWIG

Holly Liske, BSAC

neuroendoscopy
Neuroendoscopy

Jenna: Could you please add references for the photos? Also, the picture on the right was pretty low resolution on the overhead – is there another one that could replace it? Otherwise, this slide looks pretty cool 

During neurosurgery, an endoscope provides real-time imaging of the cranial surface and a port for introducing surgical instruments

problem definition
Problem Definition
  • A non-peristaltic flow of saline over the cranial surface clears debris for visualization of the surgical field
  • Flow is disrupted with the introduction of surgical instruments
    • 30-75% change in flow rate
    • Flooding and poor visibility
client requirements
Client Requirements
  • Centrifugal pump modulates saline flow
    • Bio-Pump®, Bio-Console®, flow sensor
design specifications
Design Specifications
  • Develop electrical interface of neuroendoscope and Bio-Pump®:
    • Bio-Pump® flow rate:
        • Current = 5.00 L/min
        • Desired = 0.15 L/min
    • Negative feedback:
        • Control of saline flow rate with insertion of surgical instruments
        • Adjustable flow and equilibration rates
        • Optimal flow rate = 85-115 mL/min
        • Error ≤ 10 mL/min
differential amplifier design
Differential Amplifier Design

Inverting operational amplifiers

Noninverting operational amplifier

Differential amplifier

slide8

VC

Vdiff

VS

differential amplifier design1
Differential Amplifier Design

Advantages

Disadvantages

  • Adjustable response through amplifier and potentiometer selection
  • Simplicity
  • Potential for negative voltage output from differential amplifier
  • Minimal adjustment of feedback rate
comparator design
Comparator Design

Magnitude comparator

Bipolar transistors

Inverting operational amplifiers

Noninverting operational amplifiers

Summing amplifier

slide11

Vs

Vs<Vc

Vs=Vc

Vs>Vc

V1

V2

V3

slide12

Vs

Vs<Vc

Vs=Vc

Vs>Vc

V1

V2

V3

slide13

Vs

Vs<Vc

Vs=Vc

Vs>Vc

V1

V2

V3

comparator design1
DisadvantagesComparator Design

Advantages

Adjustable feedback rate

Resilience to all comparisons of Vs and Vc

Smooth equilibration

  • Relative complexity
future work
Future Work
  • Select components to optimize feedback
  • Purchase and assemble components
  • Integrate with existing equipment
  • Test and evaluate design
    • Monitor flow rate with introduction of surgical instruments
  • Develop customized control of Bio-Console®