BROOKLYN 3 STUDENTS Adam ROSCOE Samuel THOMAS. Fri 30 th Aug 2013 Session 2 / Talk 5 11:25 – 11:35. ABSTRACT
Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.
Adam ROSCOE Samuel THOMAS
Fri 30thAug 2013
Session 2 / Talk 5
11:25 – 11:35
A short presentation on Gouty arthritis, to help further our understanding of a common indication seen on Xray requests. In our presentation we are going to cover the basics of Gout, including a definition, pathological classification, history and nature of this joint pathology, and also clinical management of patients suffering from Gout.
Gout is a type of arthritis that results from an inflammatory response to a build up of uric acid in the vascular system progressing to erosion of the articulating surfaces of bones. It is an inherited metabolic disease and is classed either as an acute or chronic condition.
Gout is more prevalent in males and can be influenced by diet and lifestyle. The pathogenesis of Gout involves the metabolism of Purines, a type of nucleic acid found in beer, fish, and mushrooms. This results in a waste product called Uric acid, which if not regulated by the Kidney, will crystallize and lead to bone erosion. Clinicians suspecting Gouty arthritis in their patient are likely to consider the patient’s history, and send for tests such as Xray or synovial joint aspirations.
Focus will be on
Anton, F., Garcia, J., Ramos, T., Gonzalez, P., Ordas, J. (1986). Sex Differences in Uric Acid Metabolism in Adults. Metabolism: Clinical and Experimetal, 35(4), 343-8. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/3959904
Dalbeth, N. (2006). The Pathway from Gout to Bone Erosion. Retrieved from http://www.hrc.govt.nz/sites/default/files/HRC69%20(Dalbeth).pdf
Doherty, M. (2009). New Insights into the Epidemiology of Gout. Oxford Rheumatology Journal, 48:ii2–ii8. doi:10.1093
Eustice, C. (2012). Cut Back Purine-Rich Foods with Gout. Retrieved from http://arthritis.about.com/cs/goutdiet/a/goutpurines.htm
Gout. (2012). Retrieved from http://www.healthinplainenglish.com/health/musculoskeletal/gout/index.htm
Gout: Exams and Tests. (2010). Retrieved from http://arthritis.webmd.com/tc/gout-exams-and-tests
Kowalczyk, N., Mace, J. (2009). Radiographic Pathology for Technologists (5th ed.) St. Louis, Missouri: Mosby Elsevier
Mandell, B. (2008). Clincal Manifestations of Hyperuricemia and Gout. Cleveland Clinical Journal of Medicine, 75(5). Retrieved from http://ccjm.org/content/75/Suppl_5/S5.full.pdf
Manno, R. (2012). Clinical Features of Gout. Retrieved from http://www.hopkinsarthritis.org/arthritis-info/gout/clinical-presentation-of-gout/
Marieb, E., Hoehn, K. (2007). Human Anatomy & Physiology (7th ed.). San Francisco, CA: Pearson Benjamin Cummings
Nuki, G., Simkin, P., (2006). A Concise History of Gout and Hyperuricemia and their Treatment. Journal of Arthritis Research and Therapy 2006, 8(1), doi:10.1186/ar1906
Stoppler, M. (2012). Gout. Retrieved from http://www.medicinenet.com/gout/page2.htm
Taylor, K. (2012). Uric Acid Crystals. Retrieved from http://www.goutpal.com/uric-acid/uric-acid-crystals/
Teitel, A. (2011). Gout. Retrieved from http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001459/
Zare, F., Magnusson, M., Bregstrom, T., Brisslert, M., Josefsson, E., Karlsson, A., Tarkowski, A. (2006). Uric Acid, a nucleic acid degredation product, down-regulates dsRNA-triggered arthritis. Journal of Leukocyte Biology, 79(3), 482-4. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/16387838