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This resource covers essential concepts in life sciences, focusing on cellular reproduction and DNA structure and function. Chapters reviewed include Cellular Reproduction and DNA, with an emphasis on meiosis, the role of DNA as an instruction manual for proteins, and the process of mutation. We explore key topics such as point mutations, codon position, and their implications in diseases like EHV-1. Additionally, we discuss the significance of germ-line mutation and differentiation. This comprehensive overview is ideal for students seeking to understand the fundamentals of genetics and its applications in health.
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BIO 110, Life Science Summer 2012
Readings • Text • Look over Chapter 8: Cellular reproduction • Look over Chapter 10: DNA • p. 186 (review the rest of the chapter) • pp. 130-140: Meiosis and sex • Wikipedia • http://en.wikipedia.org/wiki/Equine_herpesvirus_1
DNA: the instruction manual • Basic structure • Replication • Genes and not-genes • A template for proteins • A template for active RNA • Regulating other DNA
Mutation • The tale of the clumsy scribe • DNA: breakable but fixable • Point mutations: substitution, addition, deletion; frame-shift • Codon position and “silent substitution” • Bigger breakage
The tale of EHV-1 • Herpesviruses • Chicken pox/shingles • Oral and genital • Dogs and horses • EHV-1 • Respiratory • Neurological: “SNP” • Stealing copies
Mutation and inheritance • Germ-line mutation • Mutation during differentiation • When mutation doesn’t matter