Involvement of Wild-Type Igh Allele in B-Cell Tumours: A Study

Jan 13, 2025

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This study discusses how genetic alterations in B-cell tumors consistently involve the wild-type Igh allele, as revealed by research conducted by Gostissa et al. in Nature. The implications of these findings are explored in depth.

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Involvement of Wild-Type Igh Allele in B-Cell Tumours: A Study

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T(12;15) in CXPR+/– B-cell tumours always involves the wild-type Igh allele. M Gostissa et al. Nature462, 803-807 (2009) doi:10.1038/nature08633

H Song et al. Nature 462 , 1039-1043 (2009) doi:10.1038/nature08 639

Gated IET spectra and linewidth broadening of a Au-ODT-Au junction. H Song et al. Nature 462 , 1039-1043 (2009) doi:10.1038/nature08 639.

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K Hase et al. Nature 462 , 226 - 230 (2009) doi:10.1038/nature08 529

GP2 binds to FimH-expressing Gram-negative bacteria. K Hase et al. Nature 462 , 226 - 230 (2009) doi:10.1038/nature08 529.

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K Hase et al. Nature 462 , 226 - 230 (2009) doi:10.1038/nature08 529

In the intestine, GP2 is exclusively expressed by mouse and human M cells. K Hase et al. Nature 462 , 226 - 230 (2009) doi:10.1038/nature08 529.

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H Yanai et al. Nature 462 , 99 - 103 (2009) doi:10.1038/nature08 512

Interference of HMGB-nucleic-acid-induced activation of innate immune responses by use of high-binding-affinity nucleotide analogues. H Yanai et al. Nature 462 , 99 - 103 (2009) doi:10.1038/nature08 512.

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NW Pierce et al. Nature 462 , 61 5 -619 (2009) doi:10.1038/nature08595

Final product distribution for SCF Cdc4 and CYCE. NW Pierce et al. Nature 462 , 61 5 -619 (2009) doi:10.1038/nature08595.

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SP Dash et al. Nature 462 , 491 -494 (2009) doi:10.1038/nature08570

Spin accumulation in n-type devices with the depletion region of the Si removed by Cs. SP Dash et al. Nature 462 , 491 -494 (2009) doi:10.1038/nature08570.

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Y Wang et al. Nature 462 , 467-472 (2009) doi:10.1038/nature08610

FocA contains two constriction sites and may exist in a closed-pore state. Y Wang et al. Nature 462 , 467-472 (2009) doi:10.1038/nature08610.

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Y Wang et al. Nature 462 , 467-472 (2009) doi:10.1038/nature08610

Features of the axial channel in the FocA protomer. Y Wang et al. Nature 462 , 467-472 (2009) doi:10.1038/nature08610.

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Y Wang et al. Nature 462 , 467-472 (2009) doi:10.1038/nature08610

The overall structure of FocA. Y Wang et al. Nature 462 , 467-472 (2009) doi:10.1038/nature08610.

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C Fang et al. Nature 462 , 200 - 204 (2009) doi:10.1038/nature08 527

FSRS spectra of wild-type GFP in D 2 O from –100 fs to 1 ps following 396-nm excitation. C Fang et al. Nature 462 , 200 - 204 (2009) doi:10.1038/nature08 527.

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DY Wu et al. Nature 462 , 1056-1060 (2009) doi:10.1038/nature08 656

Maximum-likelihood phylogenetic tree of the bacterial domain based on a concatenated alignment of 31 broadly conserved protein-coding genes 16 . Phyla are distinguished by colour of the branch and GEBA genomes are indicated in red in the outer circle of species names.

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M Santos-Lleo et al. Nature 462 , 997-1004 (2009) doi:10.1038/nature08 690

Portion of an XMM-Newton reflection-grating spectrum of the disk of Mars. M Santos-Lleo et al. Nature 462 , 997-1004 (2009) doi:10.1038/nature08 690.

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M Santos-Lleo et al. Nature 462 , 997-1004 (2009) doi:10.1038/nature08 690

Chandra (2   2  ) images detailing the expanding and brightening ring surrounding the stellar explosion SN 1987A. M Santos-Lleo et al. Nature 462 , 997-1004 (2009) doi:10.1038/nature08 690.

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M Santos-Lleo et al. Nature 462 , 997-1004 (2009) doi:10.1038/nature08 690

Chandra image of Centaurus A. M Santos-Lleo et al. Nature 462 , 997-1004 (2009) doi:10.1038/nature08 690.

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Y Qi et al. Nature 462 , 762-766 (2009) doi:10.1038/nature08 561

Free energy profiles of nucleobase extrusion imply active participation of MutM. Y Qi et al. Nature 462 , 762-766 (2009) doi:10.1038/nature08 561.

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T Hakoyama et al. Nature 462 , 514 -517 (2009) doi:10.1038/nature08594

Complementation of fen1 mutants by inoculation with Mesorhizobium loti carrying FEN1 and Azotobacter vinelandii NifV. T Hakoyama et al. Nature 462 , 514 -517 (2009) doi:10.1038/nature08594.

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G Gouridis et al . Nature 462 , 363 - 367 (2009) doi:10.1038/nature08 559

Signal peptides added in trans promote PhoA translocation. G Gouridis et al . Nature 462 , 363 - 367 (2009) doi:10.1038/nature08 559.

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Y Qi et al. Nature 462 , 762-766 (2009) doi:10.1038/nature08 561

OxoG-dependent local DNA structure alterations at the site of the target base in EC3 and EC5. Y Qi et al. Nature 462 , 762-766 (2009) doi:10.1038/nature08 561.

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Y Qi et al. Nature 462 , 762-766 (2009) doi:10.1038/nature08 561

R112-catalysed oxoG extrusion. Y Qi et al. Nature 462 , 762-766 (2009) doi:10.1038/nature08 561.

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Y Galanty et al. Nature 462 , 935-939 (2009) doi:10.1038/nature08657

SUMOs and UBC9 accumulate at DNA-damage sites by mechanisms requiring MDC1, 53BP1 and BRCA1. Y Galanty et al. Nature 462 , 935-939 (2009) doi:10.1038/nature08657.

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M Guo et al. Nature 462 , 808 -8 12 (2009) doi:10.1038/nature08612

Plasticity of active site in AlaRS. M Guo et al. Nature 462 , 808 -8 12 (2009) doi:10.1038/nature08612.

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H Song et al. Nature 462 , 1039-1043 (2009) doi:10.1038/nature08 639

Resonantly enhanced IET spectra of a Au-BDT-Au junction. H Song et al. Nature 462 , 1039-1043 (2009) doi:10.1038/nature08 639.

82 views • 1 slides

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