1 / 18

Organic chemistry A Chapter 4 Stereochemistry By Prof. Dr. Adel M. Awadallah

Organic chemistry A Chapter 4 Stereochemistry By Prof. Dr. Adel M. Awadallah Islamic University of Gaza. Stereochemistry Isomers : different compounds having the same molecular formula. A chiral molecule is one that is optically active

tjoan
Download Presentation

Organic chemistry A Chapter 4 Stereochemistry By Prof. Dr. Adel M. Awadallah

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. Organic chemistry A Chapter 4 Stereochemistry By Prof. Dr. Adel M. Awadallah Islamic University of Gaza

  2. Stereochemistry Isomers: different compounds having the same molecular formula

  3. A chiral molecule is one that is optically active • A racemic mixture (racemic modification) is one with equal ratios of enantiomers (50:50 mixture)

  4. Configuration and the R-S Convention

  5. Examples

  6. Compounds with more than one stereogenic center; (Diasteriomers)

  7. Properties of enantiomers and diastereomers • A) Enantiomers • Have the same physical properties except for direction of rotation of plane polarized light • Have the same chemical properties except for their reaction with other chiral molecules • (This usually seen in their biological activity) • B) Diastereomers • Have different physical properties • Similar chemical properties

  8. Chemical reactions of stereoisomers • 1) Generation of a chiral center

  9. Reaction away from a chiral center

  10. Generation of a second chiral center

  11. Resolution of enantiomers • Enantiomers + chiral molecules gives diasteriomers which can be sepearated, then we get red of the chiral molecules

More Related