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Types of nucleic acids DNA: In nucleus but some in the mitochondria Replicated to form copy of DNA in cell division; Transcribed to form RNA RNA: In nucleus and mitochondria and cytoplasm. rRNA – ribosomal RNA for ribosome for translation of mRNA to form protein

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slide1

Types of nucleic acids

  • DNA: In nucleus but some in the mitochondria
    • Replicated to form copy of DNA in cell division;
    • Transcribed to form RNA
  • RNA: In nucleus and mitochondria and cytoplasm.
    • rRNA – ribosomal RNA for ribosome for translation of mRNA to form protein
    • mRNA – messenger RNA translated to from protein
    • miRNA – microRNA chemically processed to a for than can bind to mRNA and inhibit translation or to DNA and alter transcription

NUCLEIC ACIDS

proteins

40s

tRNA, miRNA genes

RNA polymerase III

rRNA gene

(in nucleolus)

RNA polymerase II

RNA polymerase I

mRNA gene

3’

ds-DNA

5’

tRNA

A site

tRNA

P site

Template, -, sense

3’

5’

pre-tRNA, miRNA

pre-rRNA

pre-mRNA

incoming

amino acid

growing

peptideprotein

ribosomal subunits

Nucleus

60s

Nuclear membrane

Cytoplasm

mRNA

tRNA

miRNA

Dicer

Ribosome

duringtranslation

X

RISC

RISC

siRNA

Rough endo. reticulum

ribosome

mitochondrion

cell membrane

cytoplasm

cytosol

dsDNA

ribosomesubunits

lysosome

pre-rRNA

ER bound

ribosome

pre-mRNA

tRNA

pre-tRNA

pre-miRNA

S-S

S-S

m7G

Mitochondrial DNA, RNA

mRNA

Signal Recog Part.

peroxisome

SRP Receptor

free

ribosome

ER-attached

ribosome

ER

Translationpost-trans modification

smooth

endoplasmic

reticulum

cell membrane

protein

free ribosome

Golgi complex