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Probability of OS (%) - PowerPoint PPT Presentation


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Stupp Trial: Improved survival with TMZ Chemotherapy. 100. 90. 80. RT + TMZ. 70. RT. 60. Probability of OS (%). 50. 40. 30. 20. 10. 0. 6. 12. 18. 24. 30. 36. 42. Months. No. at Risk. RT 286 240 144 59 23 2 0 RT+TMZ 257 216 174 109 57 27 4

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slide1

Stupp Trial: Improved survival with TMZ Chemotherapy

100

90

80

RT + TMZ

70

RT

60

Probability of OS (%)

50

40

30

20

10

0

6

12

18

24

30

36

42

Months

No. at Risk

RT 286 240 144 59 23 2 0

RT+TMZ 257 216 174 109 57 27 4

HR 0.63 (95% Cl, 0.52 to 0.75; p<0.001)

Adapted from Scrive et al. ASTRO 2007

slide2

Long-term Survival

Adapted from Mirimanoff et al. ASTRO 2007.

slide3

MGMT Gene Status: Survival at Four Years

Adapted from Mirimanoff et al. ASTRO 2007.