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Improved Survival Rate with TMZ Chemotherapy: Stupp Trial Analysis
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Stupp Trial analysis reveals enhanced survival outcomes with TMZ chemotherapy for patients with MGMT gene alteration. Results demonstrate significant impact on overall survival rates, validating the efficacy of combined treatment.
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Improved Survival Rate with TMZ Chemotherapy: Stupp Trial Analysis
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Presentation Transcript
Stupp Trial: Improved survival with TMZ Chemotherapy 100 90 80 RT + TMZ 70 RT 60 Probability of OS (%) 50 40 30 20 10 0 6 12 18 24 30 36 42 Months No. at Risk RT 286 240 144 59 23 2 0 RT+TMZ 257 216 174 109 57 27 4 HR 0.63 (95% Cl, 0.52 to 0.75; p<0.001) Adapted from Scrive et al. ASTRO 2007
Long-term Survival Adapted from Mirimanoff et al. ASTRO 2007.
MGMT Gene Status: Survival at Four Years Adapted from Mirimanoff et al. ASTRO 2007.
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