bone morphogenetic protein l.
Download
Skip this Video
Loading SlideShow in 5 Seconds..
Bone Morphogenetic Protein PowerPoint Presentation
Download Presentation
Bone Morphogenetic Protein

Loading in 2 Seconds...

play fullscreen
1 / 8

Bone Morphogenetic Protein - PowerPoint PPT Presentation


  • 539 Views
  • Uploaded on

Bone Morphogenetic Protein. By: Kim Stephens. What is Bone M orphogenetic P rotein?. Stimulates a patient's own cells to induce the formation of  bone and cartilage Recombinant human bone morphogenetic protein-2 , or rhBMP-2 Generates and repairs bone faster and more reliably

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'Bone Morphogenetic Protein' - thadeus


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
what is bone m orphogenetic p rotein
What is Bone Morphogenetic Protein?
  • Stimulates a patient's own cells to induce the formation of bone and cartilage
  • Recombinant human bone morphogenetic protein-2, or rhBMP-2
  • Generates and repairs bone faster and more reliably
  • Latest in bone growth enhancement
changing points
Changing Points

1965: Dr. Marshall Urist, UCLA Department of Orthopedic Surgery in Los Angeles, CA discovered that the proteins needed to heal bone was inside bones

1997: First clinical trial with 11 patients

2001: New Hampshire Spine Institute

applications
Applications
  • Available in an oral form
    • A supplement for bone and joint health

Regenerative Medicine:

  • Delivered to the site of the fracture
  • Released gradually to allow bone formation
  • Delivery in a purified collagen matrix
potential applications
Potential Applications
  • Osteoinductive characteristics make BMPs valuable as an alternative to bone grafts
  • Other methods of delivering BMPs to patients are undergoing evaluation
  • Non-skeletal tissues
  • Organogenesis
slide6
Advantages

Disadvantages

BMP has only been FDA approved for one type of spinal fusion

Expensive

Side effects are not fully understood

  • Less pain, shorter hospital stays
  • More rapid return to a normal life
  • As effective as bone grafts
  • Eliminate the need for bone transplantation
  • Avoids the potential side effects and complications of bone harvesting or grafts
future
Future
  • Use of BMP will potentially extend beyond skeletal disease and injury
  • Approval from the FDA to use BMP’s for dental work
  • Better understand these proteins and their benefits
works cited
Works cited
  • http://www.spineuniverse.com/treatments/surgery/spinal-fusion-bone-morphogenetic-protein
  • http://www.spineuniverse.com/exams-tests/bone-morphogenetic-protein-bmp
  • http://www.medscape.com/viewarticle/446738_3
  • http://www.zycalbio.com/research.htm
  • http://en.wikipedia.org/wiki/Bone_morphogenetic_protein
  • http://www.spine-health.com/treatment/spinal-fusion/bmp-bone-morphogenetic-proteins
  • http://www.freepatentsonline.com/4294753.html
  • http://webapps.css.udel.edu/biotech/rDNA.html
  • http://www.sciencedirect.com/science/article/pii/S0006291X07017147