Insights into Endothelial Dysfunction and Unstable Plaque: Research Highlights from Euregio

Dec 16, 2025

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This article discusses key findings from the Euregio Cardiovascular Research initiative, focusing on endothelial dysfunction and its implication in leukocyte adhesion, unstable plaque rupture, and thrombosis. Notable works by researchers Libby, Ridker, and Hansson are highlighted, showcasing their contributions to understanding the mechanisms behind fibroproliferative growth in cardiovascular diseases. The discussion is anchored on selected research milestones from IRTG1508, emphasizing the collaborative efforts between RWTH Aachen University and Maastricht University, and the implications for future cardiovascular therapies.

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Insights into Endothelial Dysfunction and Unstable Plaque: Research Highlights from Euregio

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EuCAR = Euregio Cardiovascular Research 29.8 km RWTH Aachen University Universitätsklinikum Maastricht University AzM
Endothelialdysfunction: Leukocyteadhesion Normal vessel wall Unstableplaque:rupture, thrombosis Fibroproliferativegrowth Libby, Ridker, Hansson, Nature 2011
Selected Research Highlights inIRTG1508