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Gross Neuroanatomy Measures and Introduction to Variability in Cerebral Sulci Identification

This study introduces variability in cerebral sulci identification using gross neuroanatomy measures. Talairach transformation, manual sulci identification, and incidence rates of major sulci are discussed. Statistical analysis is performed on 30 hemispheres from 15 individuals, showing displacement in major sulci. The study provides insights into the location of central sulcus and incidence rates of sulci. Data collection involved tomographic imaging, landmarks alignment, and projection of sulci.

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Gross Neuroanatomy Measures and Introduction to Variability in Cerebral Sulci Identification

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  1. Gross neuroanatomy measures &introduction to variability References Steinmetz H., Furst, G., Freund, H., “Cerebral Cortical Localization: application and validation of the proportional grid system in MR Imaging”, 1989, Journal of Computer Assisted Tomography, 13(1):10-19 Ono M., Kubik S., Abernathey C.D., Atlas of the cerebral sulci, 1990, Thieme Verlag

  2. Talairach transformation&variability range of main sulci

  3. Method • Tomographic images are collected on 30 hemispheres of 15 people (22-63 yo) • Talairach transformation is performed using 4 AC PC and 5 extreme landmarks • Sulci are identified manually and projected sagitally Shift AC PC vertically and side-to-side Align extreme points AC AC PC PC

  4. Leftover variability after Talairach transformation Calossal, Parietooccipital, Marginal sulci, 30 hemispheres Central Sulcus 20 hemispheres Sylvian Fissure (L) 15 hemispheres Sylvian Fissure (R) 15 hemispheres

  5. Summary • Central sulcus (CS) in the postmortem Talairach brain is located 0.5-1.0 cm anterior to the CS in the 30 hemispheres studied here • 2-3 cm displacement is observed in most of the studied major sulci

  6. Incidence rates of main sulci

  7. Method • 25 postmortem brains • Length determined by running a chord inside sulci • Molded silicon models are developed to study internals of the sulci

  8. Statistics

  9. Statistics

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