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Dr. Tina Dewi J , dr., SpOG Dept Epidemiology and Biostatistics

EBM – therap y. Dr. Tina Dewi J , dr., SpOG Dept Epidemiology and Biostatistics Padjdjaran University School of medicine. Diagnostic test. Harm. cost-effective. Therapeutic or Intervention. S.R. & others. prognosis. Worksheets. General Overview. Worksheet. Is the result VALID?

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Dr. Tina Dewi J , dr., SpOG Dept Epidemiology and Biostatistics

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  1. EBM – therapy Dr. Tina Dewi J , dr., SpOG Dept Epidemiology and Biostatistics Padjdjaran University School of medicine

  2. Diagnostic test Harm cost-effective Therapeutic or Intervention S.R. & others prognosis Worksheets General Overview

  3. Worksheet • Is the result VALID? • Randomized assignment? • Was follow-up complete? • Patients are analyzed in the assigned group • Double-blind • Groups similar at the start of the trial? • Aside from the experimental intervention, were the groups treated equally? • How large was the treatment effect?

  4. Therapeutic (Rx) WorksheetCan We Apply it to our Pts? • Will the results help me in caring for my patients? • Can the results be applied to my patients? • Rx/intervention AVAILABLE in our setting. • Were all clinically relevant outcomes considered? • Are the benefits worth the harm and cost?

  5. Tools Used in Rx WorksheetRelative Risk (RR)

  6. For the relative risk (RR), the same applied RR is calculated the rate of exposed or treated divided by those not exposed or treated CI is used to calculate the magnitude of the treatment / intervention effect. Tools Used in Rx WorksheetRelative Risk (RR)

  7. Tools Used in Rx WorksheetRelative Risk (RR) Control event rate (CER) = 10 / 100 =10% Experimental event rate (EER) = 3 / 100 =3% RR = EER/CER =3% / 10% =33 % RRR = CER – EER / CER =10% - 3% / 10% = 70 % ARR = CER – EER = 10% - 3% = 7 % NNT = 1/ARR =1 / 7 x100 =15

  8. Tools Used in Rx Worksheet Confidence interval • Is the result of the study true for the whole population? • It specifies how far above or below a sample-based value the population value lies. • The smaller the size of the study = the wider confidence interval.

  9. Read the discussion • Did they make good reasoning for the findings • Any other trial that support the study results. • Any other study that contradict the result.

  10. Read the conclusions • Are the objectives met? • Is there any recommendations? • Any mention about limitations of the study?

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