html5-img
1 / 6

Excitable Tissues- Synapse

Excitable Tissues- Synapse. Prof. K. Sivapalan. Synapses. Two or more neurons communicate through synapse. Communications are formed with the cell body, dendrides or with the axon sometimes. Structure of a synapse. Pre-synaptic and post synaptic membrane Synaptic cleft- 20-40 nm.

tacita
Download Presentation

Excitable Tissues- Synapse

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Excitable Tissues- Synapse Prof. K. Sivapalan

  2. Synapses • Two or more neurons communicate through synapse. • Communications are formed with the cell body, dendrides or with the axon sometimes. Synapse

  3. Structure of a synapse • Pre-synaptic and post synaptic membrane • Synaptic cleft- 20-40 nm. • Synaptic vesicles- transmitter • Transmitters released by exocytosis and recovered by endocytosis or destroyed by enzymes Synapse

  4. Sequence of Events at the Axon Terminal • Action potential arrives in the axon • Voltage gated calcium channels at the pre-synaptic membrane open and calcium ions enter • Calcium activates release of synaptic vesicles • Synaptic vesicles cross the cleft and bind with the receptors in the post synaptic membrane. Synapse

  5. Events at the Post Synaptic Membrane • The transmitters released in the cleft bind with receptors in the post synaptic membrane • The transmitter may increase the conductivity (permeability) of cl- or Na+ [sometimes Ca++] • Ligand gated channels • This leads to entry of the respective ion into the ICF resulting in change in membrane potential. • Entry of cation alters the potential towards threshold level [EPSP] and anion causes hyper polarization [IPSP] • EPSP and IPSP from multiple synapses [spacial] or repeated [temporal] release from the same synapse are summated. Synapse

  6. Genesis of action potential in Post Synaptic Neuron Synapse

More Related