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ATHEROSCLEROSIS5

atherosclerosis

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ATHEROSCLEROSIS5

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  1. ATHEROSCLEROSIS

  2. ATHEROSCLEROSIS

  3. ATHEROSCLEROSIS • It is commonly referred to as a hardening or furring of the arteries.• It is caused by the formation of multiple plaques within the arteries.• It can restrict blood flow. These plaques can also burst, causing a blood clot.• Although atherosclerosis is often considered a heart problem, it can affect arteries anywhere in your body.• Atherosclerosis is a preventable and treatablecondition.

  4. TERMS • Arteriosclerosis is a general term describing any hardening (and loss of elasticity) of medium or large arteries • Arteriolosclerosis is any hardening (and loss of elasticity) of arterioles (small arteries); • Atherosclerosis is a hardening of an artery specifically due to an atheromatous plaque. • Atherogenic is used for substances or processes that cause atherosclerosis. • Atherogenesis is the developmental process of atheromatous plaques

  5. CAUSES • High blood pressure• High cholesterol• An irritant, such as nicotine• Certain diseases, such as diabetes

  6. Pathophysiology • Atherosclerosis develops as a chronic inflammatory response of the arterial wall to endothelial injury.• Lesion progression occurs through interactionsof modified lipoproteins, monocyte-derived macrophages, T-lymphocytes, and the normal cellular constituent of the arterial wall.

  7. The contemporary view of atherosclerosis isexpressed by the response-to-injury hypothesis.

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  12. ComplicationsThe complications of atherosclerosis depend on thelocation of the blocked arteries. For example: Coronary artery disease. Atherosclerosis narrows the arteries close to your heartCarotid artery disease. Atherosclerosis narrows the arteries close to your brain Peripheral artery disease. Atherosclerosis narrows the arteries in your arms or legs. Aneurysm An aneurysm is a bulge in the wall of your artery.

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