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Phantom Simulation of Liver Motion During Breathing

Phantom Simulation of Liver Motion During Breathing. Group Members: Ian Dallmeyer Tuta Guerra Ian Henderlong Advisor: Dr. Bob Galloway. Background. Over 225,000 people in the U.S. diagnosed with primary or metastatic liver cancer in 2003. Cancers often spread throughout the liver.

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Phantom Simulation of Liver Motion During Breathing

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  1. Phantom Simulation of Liver Motion During Breathing Group Members: Ian Dallmeyer Tuta Guerra Ian Henderlong Advisor: Dr. Bob Galloway

  2. Background • Over 225,000 people in the U.S. diagnosed with primary or metastatic liver cancer in 2003. • Cancers often spread throughout the liver. • Traditional surgery difficult/not possible. • No IGS techniques for the abdomen. • Respiratory motion • Pigs • Liver structure different than humans.

  3. Problem • Need an anatomically correct model which accurately simulates liver motion due to breathing to test IGLS techniques.

  4. Advantages of Phantom Model • Porcine Liver • Approx. $1,000 – $2,000 per liver • Not anatomically correct • Not reusable • Phantom model • Anatomically correct • Reusable • Time and space-saving

  5. Alternatives to Modeling Liver Motion • High-Frequency Jet Ventilation • Disadvantages • Maximum Duration of 45 min. • Cardiovascular Complications • Patient Response • Expensive

  6. Market Potential • Current methods too invasive • Open liver resection • Estimated market for IGLS 10x current IGNS market • IGLS: $3.0-$7.5 billion • Reusable model needed to perfect IGLS techniques

  7. Phantom Liver • Equipment • Liver • Muscle Wire • PVC Pipe • Power Source • Sliding Mechanism System • Spring/Rubber Band/Elastic for Recoil

  8. Ideal Design

  9. Shape Memory Alloy • Shape memory alloys deform upon heating • Martensite – low T, soft, deformable • Austenite – higher T, hard, non-deformable • Other SMA’s - CuZnAl, and CuAlNi

  10. Design Specs • 1-D Linear motion (cranial- caudal) • 10.8 + 2.5 mm (ATLM) • Breath Frequency ~= .11 Hz. (1 breath/9 sec)

  11. Current Work • Cart construction • Force determination • Testing of recoil strategies

  12. Future Work • Purchase/Testing of muscle wire • Construction of power source • Assemble liver in PVC pipe

  13. References • Herline AJ, Stefansic JD, Debelak JP, Hartmann SL, Wright Pinson C, Galloway RL, Chapman WC. Image Guided Surgery: Preliminary; Feasibility Studies of Frameless Stereotactic Liver Surgery. June 1999 Archives of Surgery 134:644-650 • Tarczy-Hornoch P, Jones D, Zerom B, Woodrum D, and Berk R. Mechanical Ventilators. [Online] Available http://weber.u.washington.edu/~neonatal/NICU-WEB/vents.html, 1998.

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