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BioMediTech. A S ource for High Q uality R esearch and Innovations. BioMediTech. Joint institute of University of Tampere & Tampere University of Technology. Over 250 scientists in world-class basic and translational research Tissue engineering and stem cell technology
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BioMediTech A Sourcefor HighQualityResearch and Innovations
BioMediTech Joint institute of University of Tampere & Tampere University of Technology Over 250 scientists in world-class basic and translational research • Tissue engineering and stem cell technology • Biomaterials • Sensor and actuator technologies • Measurement and imaging technologies • Biotechnology • Immunology • Cancer and mitochondrial research • Systems biology • Bioinformatics • Computational methods in biomedicine
Kauppi University Campus Orig. http://www.pshp.fi/
Aiming for Excellence BioMediTech • aims for excellence in • education • basicresearch • translationalresearch • housesstate-of-the-artlaboratories and 200m2GMP-levelcleanrooms • EMEA approved GMP stemcellproductionunit
Example of Research Excellence • BioMediTech: • world leader in stem cell based reconstructions of cranial bones • 22 cases operated • combination of biomaterials and stem cells differentiated from subcutaneous fat • Nearly 20 M€ project funding for Human Spare parts program (2011-2015) • Development of tissue engineering products and supporting technologies • Tekes, Academy of Finland, Council of Tampere Region, EU 2 months post op 28 months post op
Adultstemcells Embryonicstemcells iPSCs Productionin GMP andownxenofree media Tissue engineering at Regea Cardiac, neural, opthalmological, soft and hardtissueapplications
Adiposestemcells Stem cells can be isolated from the patient’s own adipose tissue, differentiated in vitro and transplanted back into the host • tissue rejections are avoided S.Miettinen
Adipose stem cells Adipose stem cells Differentiate to.... • Adipocytes • Osteocytes • Chondrocytes • Tendocytes and also to • Neuralcells? • (Cardio)myocytes? • Hepatocytes? • Epi/Endothelialcells? Adapted from www.nationalacademies.org/stemcells, Wellen and Hotamisligil 2003, Hotamisligil 2006 by Bettina Lindroos
Neurosurgery Tampere UniversityHospital: Prof. Juha Öhman
Adiposestemcells and biomaterial hASC,β- TCP