1 / 20

Antihypertensive Drugs

Antihypertensive Drugs. ACE inhibitor Alpha Blockers ARBs Beta bl0ckers CCBs Thiazide Diuretics. Mechanisms of Actions. ACE inhibitors Block the conversion of angiotensin I to angiotensin II by inhibiting angiotensin converting enzyme (ACE) Alpha-blockers

solada
Download Presentation

Antihypertensive Drugs

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Antihypertensive Drugs • ACE inhibitor • Alpha Blockers • ARBs • Beta bl0ckers • CCBs • Thiazide Diuretics

  2. Mechanisms of Actions • ACE inhibitors • Block the conversion of angiotensin I to angiotensin II by inhibiting angiotensin converting enzyme (ACE) • Alpha-blockers • Lower by by reducing the peripheral resistance • Angiotensin II antagonists • Block type I angiotensin II receptors

  3. Mechanism of Action • Beta-blockers • Competitive antagonists of the effects of catecholamines at beta-adrenergic receptor sites • Thiazide Diuretics • Blocks renal tubular reabsorption of Na leading to urinary Na loss

  4. Mechanism of Action • Calcium Antagonists • Inhibit the cellular influx of Ca which is responsible for maintenance of the plateau phase of the action potential • The cells they affect are typically the vascular smooth muscle, myocardial cells and cells within the SA and AV nodes • They dilate coronary and peripheral arteries with little or no effect on venous tone, have a-veinotropic action, reduce HR and slow AV conduction

  5. P-Drug • ACE INHIBITORS • ARBs

  6. ACE Inhibitors • Captopril • Enalapril • Lisonopril

  7. Angiotensin Receptor Blockers • Losartan • Telnisartan • Valsartan

More Related