Case Presentation. Gerrit Blignaut Diagnostic Radiology UFS 17/08/2012. History. 3Y6M girl from Lesotho. 3D history of right hemiparesis, preceded by 3D history of vomiting. No previous hospital admission or any other illnesses. Father passed due to TB 3 years ago.
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3Y6M girl from Lesotho.
3D history of right hemiparesis, preceded by 3D history of vomiting.
No previous hospital admission or any other illnesses.
Father passed due to TB 3 years ago.
2 Siblings, both healthy
CNS: Right hemiparesis with power 4/5.
CVS, Resp, Abd, ENT: NAD
Bloods: FBC, U&E, HIV normal
MRI; Solid: Isointense T1 and hyperintense on T2 compared to gray matter.
Rare glial neoplasms,0.45-2.8% of primary glial tumors.
Present as a large well demarcated, supratentorialhemispheric mass.
Prefer frontoparietal region.
Children, adolescents and young adults.
Median age 11 years.
Occasional punctate Ca++
Heterogeneous enhancement: Rim of cystic
Little peritumoraledema on T2.
Mixed signal after contrast administration.
Cell of origin has features of both astrocytoma and ependymoma.
Tancytes, variety of ependymal cells.
Present in the floor of 4th ventricle.
Perivascular pseudorosettes: Astrocytic cell processes
radiate toward a central, often hyalinized blood vessel
1: Astroblastoma: A Radio-histological diagnosis J PediatrcNeurosciVol 3 2008.
2:Astroblastoma: A Rare Glial Tumor International Journal of Pathology; 2004; 2(2):100-102
3: Astroblastoma: Radiologic-Pathologic Correlation and Distinction from EpendymomaAJNR Am J Neuroradiol23:243–247, February 2002