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All You Need To Know About Melphalan

Melphalan 50 mg Injection should be given to you with the help of a needle, directly into a vein (IV), by a specially trained healthcare professional.

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All You Need To Know About Melphalan

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  1. All You Need To Know About Melphalan Melphalan is indicated to used in adult patients:  In order to relieve the symptoms caused by the multiple myeloma, a type of cancer of the blood.  In order to relieve the symptoms caused by ovarian cancer (epithelial carcinoma of the ovary) that is difficult to be removed by the surgery.  In combination with surgery for the treatment of skin cancer (malignant melanoma).

  2. How to take Melphalan Injection • Melphalan 50 mg Injection should be given to you with the help of a needle, directly into a vein (IV), by a specially trained healthcare professional.  • Usual adult dose: Your healthcare provider will determine your dose based on your weight and height. Your dose can be changed based on how well you are responding to treatment and outcome of your blood test.

  3. Side Effects Possible side effects may include: • In women, periods may stop  • In men, reduced production of sperm. • Nausea • vomiting, diarrhea  • Mouth ulcers or sori  • Hair loss  • Skin rash or itching  • Mild pain or irritation where Melphalan Injection was injected  • Flushing • Feelings of warmth or tingling  • Muscle pain, wasting, or scarring 

  4. How Does Melphalan Work Melphalan 50 mg is an alkylating agent of the bis chloroethylamine type. As an outcome, its cytotoxicity seems to be related to the extent of its interstrand cross-linking with DNA, most probably by binding at the N7 position of the guanine. Like the rest bifunctional alkylating existing agents, this one is quite active against both resting and quickly dividing tumor cells.

  5. Interact with Melphalan for Injection • Nalidixic acid:Basically an antibiotic used in order to treat bacterial infections.  • Cyclosporine, recommended to prevent organ rejection in those patients who have had an organ transplant.  • Busulfan  • Vaccination with live vaccines. Do not use Melphalan Injection if:  • you think that you are allergic to it, chlorambucil or any kind of the other existing ingredients in Melphalan Injection.  • your disease is not responding with the treatment of Melphalan.  • you are currently taking or have recently taken chemotherapy or radiotherapy.  • you have recently received a treatment with the drugs similar to the Melphalan Injection.  • you have very low platelet counts or a neutrophil (neutrophils and platelets are basically blood cells). 

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