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Epidemiology in the Hospital Setting Benjamin A. Rybicki, PhD Senior Scientist, Henry Ford Hospital Henry Ford Health System Cardiovascular Respiratory Research Cancer Human Populations Molecular Bio Epidemiology Epidemiologists Neuro Statistics Population Database Laboratory

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epidemiology in the hospital setting
Epidemiology in the Hospital Setting

Benjamin A. Rybicki, PhD

Senior Scientist, Henry Ford Hospital

slide5

Cardiovascular

Respiratory

Research

Cancer

Human Populations

Molecular Bio

Epidemiology

Epidemiologists

Neuro

Statistics

Population Database

Laboratory

Prog/Data Mgrs.

Molecular Biology

Laboratory

Mol Biologists

Statistics

Biostatisticians

Epidemiology

Interviewers

Abstractors

Data Entry

Biostatistics & Research Epidemiology

www.henryford.com/body.cfm?id=39207

bre organizational structure
BRE Organizational Structure

Biostatisticians

13

Epidemiologists

16

Molecular Epid Research Lab

6

Data Management & Programming

10

Abstracting, Interviewing, RN/LPNs, MAs

36

Data Entry

2

Computer Facility

4

Secretarial

3

Project Support

10

Grants Managers

2

Administrative Manager

1

Total Staff

103

a nested case control study using a pathology based cohort

Benign Cohort

1990 – 2006

N=8,117*

PSA test +/- 1 year of benign specimen (N=7,122)

Prostate cancer diagnosis on or before 12/31/2010

Yes

No

Cases

N=1,441

Controls

N=5,681

≥ 1 year between benign specimen and cancer diagnosis

N=1,136

≥ 1 year of follow-up after benign biopsy

N=4,431

Case-Control Matching:

Age, race, and follow-up duration

800 case-control pairs

Benign tissue available for study

N=931

Benign tissue available for study

N=3,633

Aim 1 &

Aim 2

Tumor tissue available for study

N=698

Aim 3

650 case-control pairs

A Nested Case-Control Study using a Pathology-based Cohort
slide10

Summary

At Henry Ford, epidemiologists lead and co-lead research in step with the mission of the health system. Biostatisticians are often co-investigators on epidemiologist-lead research, but focus most on statistical issues across multiple projects.• Epidemiologists tend to favor observational studies, but often employ methodologies developed by basic science researchers and team with clinical researchers doing intervention studies. • Investigators who want to use population data to address a research question can benefit from interactions with an epidemiologist.