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. The Cochrane Collaboration. Preparing, maintaining and disseminating systematic reviews of the effects of health care. Archie Cochrane. 1941 - 6 months in Salonica as the only medic. 20,000 POWs - diets of about 600 cals/day.

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The cochrane collaboration l.jpg

The Cochrane Collaboration

Preparing, maintaining and disseminating

systematic reviews of the effects of health care



Archie cochrane l.jpg

1941 - 6 months in Salonica as the only medic.

20,000 POWs - diets of about 600 cals/day.

Epidemics of typhoid, diphtheria, sand-fly fever etc. There was jaundice, and everyone had diarrhoea.

In a ramshackle hospital - only aspirin, antacids and some skin antiseptic.

He expected hundreds to die of diptheria alone

Archie Cochrane


Archie cochrane4 l.jpg

There were only 4 deaths

3 due to gunshot wounds.

Archie Cochrane


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“This excellent result had, of course, nothing to do

with the therapy they received or my clinical skills.

It demonstrated, on the other hand, very clearly the

relative unimportance of therapy in comparison

with the recuperative powers of the human body.”

Archie L Cochrane, 1972, p5

‘Effectiveness and Efficiency: Random Reflections on Health Services’


Archie cochrane6 l.jpg

Soviet POW who was dying in great pain. He was screaming and Archie had no drugs to help.

Instinctively, Archie sat on the bed and took the Russian in his arms.

The effect was almost magical, the Russian quietened at once and died peacefully a little later.

Archie Cochrane


Archie cochrane7 l.jpg

Archie C believed his personal and Archie had no drugs to help.

intervention he had improved this

soldier’s quality of life/dying very

dramatically, even though he did not

affect the final outcome.

Archie Cochrane


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“I believe that cure is rare while the need for and Archie had no drugs to help.

care is widespread, and that the pursuit of

cure at all costs may restrict the supply of

care...”

Archie L Cochrane, 1972, p7

‘Effectiveness and Efficiency: Random Reflections on Health Services’


Archie cochrane9 l.jpg

He began to Q the effectiveness of the care/treatments he offered. Did they actually worked?

He became convinced of the importance of RCTs in assessing whether a form of care/treatment worked or not.

Archie Cochrane


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“It is surely a great criticism of our offered. Did they actually worked?

profession that we have not organised a

critical summary, by speciality and

subspeciality, adapted periodically, of all

relevant randomised controlled trials”

Archie L Cochrane, 1979

‘Medicines for the year 2000’ London. Office for Health Economics. p1-11


Slide11 l.jpg

The story of the Cochrane Library offered. Did they actually worked?

  • 1972‘Effectiveness and efficiency: Random

    Reflections on Health Sciences’

    by Archie Cochrane

  • Archie awarded the wooden spoon to

    obstetricians

  • 1973 Iain Chalmers, an obstetrician, read Archie’s

    book and decided to take up the challenge


Iain chalmers l.jpg
Iain Chalmers offered. Did they actually worked?


The story of the cochrane library l.jpg

1974 offered. Did they actually worked? Iain Chalmers began a card file of references of

controlled trials in perinatal medicine

1984 Over 3,000 trials listed and coded

1985 Published ‘Classified bibliography of controlled

trials in perinatal medicine 1940-1984’ (book)

1986 Commissioned systematic reviews

The story of the Cochrane Library


The story of the cochrane library14 l.jpg

1987 offered. Did they actually worked? Letters to 42,000 obstetricians in 20 countries

seeking unpublished trials

1988 Published ‘Oxford database of perinatal trials’

(ODPT) on disc

1989 Published ‘Effective care in pregnancy and

childbirth’ (ECPC) and ‘Guide to effective care

in pregnancy and childbirth (GECPC)

15 years from beginning to collect the references

The story of the Cochrane Library


The story of the cochrane library15 l.jpg

1993 offered. Did they actually worked?Foundation of the Cochrane Collaboration

1993 Publication of the Cochrane Pregnancy &

Childbirth database (CCPC)

1995 Publication - Cochrane Database of Systematic

Reviews (CDSR)

1996 Publication of the Cochrane Library (CLIB)

22 years from beginning to collect the references

The story of the Cochrane Library


The cochrane library l.jpg

Cochrane Database of Systematic Reviews (CDSR) offered. Did they actually worked?

Database of Abstracts of Reviews of Effectiveness (DARE)

Cochrane Central Controlled Trials Register (CENTRAL)

Cochrane Database of Methodology Reviews

Cochrane Methodology Register (CMR)

About the Cochrane Collaboration

Health Technology Assessment Database (HTA)

NHS Economic Evaluation Database (NHS EED)

The Cochrane Library


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About 6000 contributors offered. Did they actually worked?

49 Collaborative Review Groups (CRGs)

12 Centres throughout the world

9 Fields

11 Methods Groups

1 Consumer Network

Campbell Collaboration

The Cochrane Collaboration


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