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This study explores the homeobox gene family across multiple species, including invertebrates like C. elegans and vertebrates such as zebrafish, catfish, pigs, and humans. We document expression levels and analyze the functional domains, such as C-terminus and N-terminus, of key homeobox genes. The research highlights the evolutionary conservation and divergence of homeobox genes, offering insights into their roles in development and physiology. Data includes expression metrics across diverse model organisms, with a focus on Oct1 and Oct2 variants.
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A. Oct1 Oct2 Invertebrate B. C. Catfish Oct1 100 Zebrafish Oct1 88 Xenopus Oct1 C-terminus N-terminus Mouse Oct1 Linker POUS POUH 90 Pig Oct1 89 Human Oct1 Catfish Oct1 72 Chicken Oct1 Zebrafish Oct1 45 94 62 90 46 Human Oct2 83 100 Mouse Oct2.1 Mouse Oct1 45 96 37 78 38 97 Pig Oct2 Mouse Oct2.1 18 94 25 76 20 Catfish Oct2a 100 Catfish Oct2β 23 93 41 80 35 Catfish Oct2b Drosophila Oct1 98 Drosophila Oct2 C. elegans homeobox