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Neurotransmission of signals

Describe the steps in neurotransmission. Describe the ionic basis for neurotransmitter release. List the major neurotransmitters and describe their mode of action. Describe the basic organization of the nervous system. Neurotransmission of signals. Conduction of Action Potentials.

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Neurotransmission of signals

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  1. Describe the steps in neurotransmission. Describe the ionic basis for neurotransmitter release. List the major neurotransmitters and describe their mode of action. Describe the basic organization of the nervous system. Neurotransmission of signals

  2. Conduction of Action Potentials Figure 8-14a: Conduction of action potentials

  3. Mechanism of Vg Na+ channels Figure 8-10: Model of the voltage-gated channel Na+

  4. Neurocrines

  5. Neurocrines

  6. Possible mechanisms of NT action

  7. Neurotransmitters and Receptors • ACh receptor (cholinergic) • nicotinic • muscarinic • NE and E receptor (adrenergic) • 1 and 2 (alpha) • 1 and 2 (beta)

  8. Acetylcholine • nicotinic receptor … is a Na+ / K+channel • muscarinic receptor … is a G-protein coupled receptor that links to 2nd messenger; five known forms

  9. http://www.blackwellscience.com/matthews/neurotrans.html

  10. Acetylcholine synthesis Figure 8-21: Synthesis and recycling of acetylcholine at the synapse

  11. Norepinephrine/Epinephrine • adrenergic receptors, alpha and beta … are G-protein coupled receptors, linked to 2nd messengers

  12. Describe the basic organization of the nervous system. List the steps in neurotransmission. Neurotransmission of signals

  13. Organization of the Nervous System Text Figure 8-1

  14. http://biology.udayton.edu/Courses/BIO415/StudyGuides/images/05/Fig11_Part_2_Movie.gifhttp://biology.udayton.edu/Courses/BIO415/StudyGuides/images/05/Fig11_Part_2_Movie.gif

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