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Does aprotinin increase the risk of renal failure in cardiac surgery patients?

Does aprotinin increase the risk of renal failure in cardiac surgery patients?. Anthony P. Furnary, MD, FAHA YingXing Wu, MD Loren F. Hiratzka, MD, FAHA Gary L. Grunkemeier, PhD U. Scott Page, MD. Providence Health Systems, Portland , OR

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Does aprotinin increase the risk of renal failure in cardiac surgery patients?