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Trna synthetases - PowerPoint PPT Presentation


Gene to Protein

Gene to Protein

Gene to Protein. What do genes do? A. Garrod’s work B. Beadle and Tatum. A. Garrod-Alkaptonuria-1902. 1. inborn error of metabolism 2. “unit factor” makes functional ferment (A) 3. recessive (a) makes nonfunctional ferment 4. AA normal Aa makes sufficient

By ophrah
(135 views)

Protein Biosynthesis

Protein Biosynthesis

Protein Biosynthesis. Away from the Ribosome Genetic code Charging tRNA Ribosomes On the Ribosome Initiation complex Elongation factors Peptide bond formation Termination. Characteristics of the Code. non-overlapping degenerate triplet

By ishana
(451 views)

The genetic code

The genetic code

Nucleic acids. Nucleic acids. Correspondence = the genetic code. Amino acids. The genetic code. Codon = triplet of three bases which encodes an amino acid. 64 possible codons = 4 3 each of 4 nucleotides can occupy each of 3 positions in the codon. Deciphering the code.

By aine
(172 views)

Protein synthesis

Protein synthesis

Protein synthesis. How a nucleotide sequence is translated into amino acids. Show unusual bases. Fig. 11-26. AA-tRNA synthetases. Enzymes that allow the correct amino acid to bind to its cognate tRNA Considered the “second genetic code”. Aminoacyl-tRNA. tRNA “charged” with amino acid

By warren-lucas
(87 views)


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tRNA Activation (charging) by aminoacyl tRNA synthetases

tRNA Activation (charging) by aminoacyl tRNA synthetases

tRNA Activation (charging) by aminoacyl tRNA synthetases. Aminoacyl tRNA synthetase. Two important functions: Implement genetic code Activate amino acids for peptide bond formation The key enzymes: Amanoacyl-tRNA synthetases. Aminoacyl-tRNA Synthesis. Summary of 2-step reaction:

By kennethroberts (0 views)

tRNA Activation (charging) by aminoacyl tRNA synthetases

tRNA Activation (charging) by aminoacyl tRNA synthetases

tRNA Activation (charging) by aminoacyl tRNA synthetases. Aminoacyl tRNA synthetase. Two important functions: Implement genetic code Activate amino acids for peptide bond formation The key enzymes: Amanoacyl-tRNA synthetases. Aminoacyl-tRNA Synthesis. Summary of 2-step reaction:

By fabienne-kael (259 views)

Common peptides study of aminoacyl-tRNA synthetases

Common peptides study of aminoacyl-tRNA synthetases

Common peptides study of aminoacyl-tRNA synthetases. Assaf Gottlieb, Milana Frenkel-Morgenstern, Mark Safro, David Horn, Plos One, 2011. * Figure from Prous science. Aminoacyl-tRNA synthetases (aaRSs). Rosetta stone. aaRS classes.

By pascal (136 views)

tRNA

tRNA

tRNA. tRNA. Transfer RNA (tRNA) is a small molecule, existing as a single-strand that is folded into a clover-leaf shape. tRNA. The role of tRNA is to bring the amino acids to a ribosome where protein synthesis is taking place. (more on this later).

By mauli (246 views)

tRNA aminoatsüleerimine

tRNA aminoatsüleerimine

tRNA aminoatsüleerimine. 1. Aminoatsüül-tRNA süntetaasid 2. Aminoatsüül-tRNA süntetaaside teised funktsioonid 3. Aminoatsüleerimise reaktsiooni skeem 4. Aminoatsüleerimise erandjuhud 5. tRNA ehitus 6. tRNA identsus 7. tRNA editeerimine e. proofreading 8. Aminohappe editeerimine.

By gyula (167 views)

tRNA-Thr

tRNA-Thr

tRNA-Thr. tRNA-Ser. tRNA-Asn. tRNA-Val. tRNA-Met. tRNA-Met. VhBAA 1627. tmRNA. tmRNA. V25X 499. tRNA-Met. Ping37 0234. VcMZO-3 1750. VpRIMD 1077. VpAQ 2450. VhHY01 00763. ShewMR-4 1686. Shew ANA3 1791. marineMeta 991. VcMZO-3 0965. VhBAA 1122. VcMZO-2 0823. Vc51 2057.

By vera (186 views)

tRNA Ser(UCN) -WT tRNA Ser(UCN) -G7497A tRNA Ser(UCN) -T7512C

tRNA Ser(UCN) -WT tRNA Ser(UCN) -G7497A tRNA Ser(UCN) -T7512C

tRNA Ser(UCN) -WT tRNA Ser(UCN) -G7497A tRNA Ser(UCN) -T7512C. G L C T1 T2 V1 S1 G L C T1 T2 V1 S1 G L C T1 T2 V1 S1. G53. G49 –G44. G39. G32. G28 G27. G24 – G21. C18. G16 G15. G13 G12. G7.

By monty (97 views)

Aminoacyl tRNA Synthetase

Aminoacyl tRNA Synthetase

Aminoacyl tRNA Synthetase. Robby Bonanno Brandon Kats Danielle Mumford. Role. Amino Acid → tRNA → Ribosome → Polypeptide chain Aminoacylates tRNA Amino Acid specificity based on anti- codon & acceptor stem of tRNA 20 synthetases for 20 commonly occuring AA’s

By page (138 views)

attB tRNA alaV

attB tRNA alaV

A. B. C. 1 2 3 4 5. D. 400 bp. 300 bp. gag. LacZ. 200 bp. pNIP46 pBlaF*-gag. pBU pBlaF*-lacZ. Ms6 derived vectors. hyg B. aph. attP. attP mut. E. X. X. BCG 1173P2. attB tRNA alaV. attB like tRNA alaU. BCG::pNIP46::pBULacZ. hyg B.

By davis (122 views)