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A Population PK/PD Model Assessing the Pharmacodynamics of a Rapid-acting Recombinant FVIIa Analogue, NN1731, in Healthy

V 2. B ? k out ? (1+ E ? C p ). Q. V 1. NN1731 dose. , ,.. Model predictions (individual) Model predictions (typical subject) o , o ,.. Observations + Mean of observations at time point. NN1731 effect. C p. F 1+2. CL. k out.

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Studied dose - PowerPoint PPT Presentation

A Population PK/PD Model Assessing the Pharmacodynamics of a Rapid-acting Recombinant FVIIa Analogue, NN1731, in Healthy