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Final

Final. Thursday May 22, 2014 Take home No help 10% extra credit Due Monday May 26, 2013 at midnight Submit to gene210.stanford@gmail.com. Discovery of new Mendelian disorders by Next Gen sequencing. Strategy. Syndrome Full Genome Sequence Look for coding mutations.

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Histone Methyltransferase Signaling Pathway

DNA and histones (H2A, H2B, H3, H4, H1) and some other proteins are combined and repeatedly folded and entangled to form a concentrated chromosome. Epigenetic modifications usually include DNA methylation and histone modification and RNA modification, while histone modifications include histone acetylation, phosphorylation, methylation, and ubiquitination. Most of the modifications are located at the N-terminus of histones.

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Final

Histone Methyltransferase Signaling Pathway