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Peripheral contractile mediators

Peripheral contractile mediators

Peripheral contractile mediators. 1-Neural factors : NA , NPY (Neuropeptid Y .) 2- Endothelial factors : ET 1 , PGF 2 ? ,Thromboxane A 2 & Angiotensin II(synthetised by penile tissue). Sm Contraction. NA, ET 1 , PGF 2 ?. Via their receptors.

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302 views • 18 slides
New Mechanistic Approaches to Myocardial Ischemia

New Mechanistic Approaches to Myocardial Ischemia

New Mechanistic Approaches to Myocardial Ischemia. New mechanistic approaches to myocardial ischemia. Rho kinase inhibition (fasudil) Metabolic modulation (trimetazidine) Preconditioning (nicorandil) Sinus node inhibition (ivabradine) Late Na + current inhibition (ranolazine).

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376 views • 16 slides
New Mechanistic Approaches to Myocardial Ischemia

New Mechanistic Approaches to Myocardial Ischemia

New Mechanistic Approaches to Myocardial Ischemia. New mechanistic approaches to myocardial ischemia. Rho kinase inhibition (fasudil) Metabolic modulation (trimetazidine) Preconditioning (nicorandil) Sinus node inhibition (ivabradine) Late Na + current inhibition (ranolazine).

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175 views • 16 slides
ROCK Signaling Pathway

ROCK Signaling Pathway

The Rho subfamily belongs to a member of the small molecule G protein in the Ras superfamily and has GTPase activity. It converts between an activated state (bound to GTP) and an inactive state (bound to GDP), acting as a molecular switch, and is a Rho protein that exerts various biological effects by binding to its downstream target effector molecule.

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18 views • 1 slides

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