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Comparative Binding Energy (COMBINE) Analysis of Barnase-Barstar Interfacial Mutants

Comparative Binding Energy (COMBINE) Analysis of Barnase-Barstar Interfacial Mutants. Binding features:. High binding affinity (Kd=10 -14 M) Polar binding interface: positive(+2e) on BN, negative (-6e) on BS Hot-spots Residues at the interface. barstar. barnase.

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Comparative Binding Energy (COMBINE) Analysis of Barnase-Barstar Interfacial Mutants