'Renal clearance' presentation slideshows

Effects of Renal Disease on Pharmacokinetics

Effects of Renal Disease on Pharmacokinetics. Juan J. L. Lertora, M.D., Ph.D. Director Clinical Pharmacology Program Office of Clinical Research Training and Medical Education National Institutes of Health Clinical Center. GOALS of Effects of Renal Disease on Pharmacokinetics Lecture.

1.14k views • 78 slides

THYROID DISEASE

THYROID DISEASE. Zachary Kuhlmann, D.O. OB/GYN Resident. Learning Objectives. Epidemiology Embryology Anatomy and Physiology Functions Pathology and Lab Changes in Pregnancy Treatment. Epidemiology. Second MC endocrine disease affecting women of reproductive age

1.57k views • 67 slides

1-C: Renal and Hepatic Elimination

1-C: Renal and Hepatic Elimination. 400 mg of moxifloxacin is administered by IV bolus to Mr BB, a 68 yr old male who weighs 75 kg. Blood samples were drawn following the dose and the plasma concentration determined. It is known that about 20% of a moxifloxacin dose is excreted in the

690 views • 60 slides

Elimination of drugs

Elimination of drugs. Electives block 2.3 (2018-19) Introduction to pharmacology - kinetics. Prof Asghar Mehdi Ph.D. Objectives. Clearance of drugs. Elimination of drugs - sites Review of renal physiology. Nature of drugs & factors affecting elimination. Drug half life

1.54k views • 50 slides

POPULATION PHARMACOKINETICS

POPULATION PHARMACOKINETICS. RAYMOND MILLER, D.Sc. Pfizer Global Research and Development. Population Pharmacokinetics. Definition Advantages/Disadvantages Objectives of Population Analyses Impact in Drug Development. Definition. Population pharmacokinetics describe

1.33k views • 43 slides

Renal Excretion of Drugs

Renal Excretion of Drugs. Prof. Hanan Hagar Pharmacology Department. Excretion of Drugs. By the end of this lecture, students should be able to Identify main and minor routes of Excretion including renal elimination and biliary excretion Describe its consequences on duration of drugs.

2.3k views • 43 slides

Basic Principles of Pharmacokinetics

1.17k views • 41 slides

Renal Physiology 3: Renal Clearance

Renal Physiology 3: Renal Clearance. Ahmad Ahmeda aahmeda@ksu.edu.sa Cell phone: 0536313454. Learning Objectives. Describe the concept of renal plasma clearance. Use the formula for measuring renal clearance. Use clearance principles for inulin, creatinine etc. for determination of GFR.

1.45k views • 39 slides

Drugs and Renal Disease

Drugs and Renal Disease. Sue Ayers Advanced Pharmacist Palliative Medicine and Chronic Pain April 2006. Overview. Effects of renal failure on ADME Renal Physiology Estimating Renal Function Dose Adjustment in Renal Impairment Principles of dialysis Drug dosing in dialysis.

1.05k views • 39 slides

Major Hemorrhagic Events (Acute Phase) No significant increase in rate of major hemorrhage

Major Hemorrhagic Events (Acute Phase) No significant increase in rate of major hemorrhage. 60. Number of patients. NS. UFH. Enoxaparin. 40. NS. NS. 20. 0. ESSENCE n = 3171. TIMI 11B n = 3910. TESSMA n = 7081. UFH, unfractionated heparin; NS, not significant.

553 views • 38 slides

Preventing Anticoagulation Errors with Clinical Dashboards

Preventing Anticoagulation Errors with Clinical Dashboards. Dan Johnson, Pharm.D ., BCPS August 3, 2011. Objectives. Describe the anticoagulant dashboards Summarize the common anticoagulant drugs and their dashboard alerts Discuss future directions in anticoagulant therapy and monitoring.

579 views • 36 slides

FREEDOM FROM RHEUMATOLOGICAL DISORDERS

FREEDOM FROM RHEUMATOLOGICAL DISORDERS. Gout An elevated serum urate concentration Recurrent attacks of acute arthritis in which MSU( monosodium urate) crystals are seen in synovial fluid Aggregates of MSU crystals (tophi) are deposited in & around joints leading to deformity & crippling

514 views • 36 slides

The Beta-Lactam Antibiotics

The Beta-Lactam Antibiotics. Cell wall active agents Prevent the final step in the synthesis of the bacterial cell wall Range from very narrow spectrum to very broad spectrum. ? -lactam ring. ? -Lactams. How do they work?. The ? -lactam binds to Penicillin Binding Protein (PBP)

1.12k views • 32 slides

Drug excretion

Drug excretion. Dr. S.O. Ogundele. Introduction. The elimination of drugs from the body involves the processes of metabolism and excretion Most drugs are metabolised first prior to being excreted

791 views • 28 slides

RENAL CLEARANCE AND RENAL BLOOD FLOW

RENAL CLEARANCE AND RENAL BLOOD FLOW. Dr.Mohammed Sharique Ahmed Quadri Al Maarefa Colege. Objective. Describe the concept of renal plasma clearance Use the formula for measuring renal clearance Use clearance principles for inulin, creatinine etc. for determination of GFR

502 views • 23 slides

PARACETAMOL POISONING:

PARACETAMOL POISONING:. Hepatic damage: more than 150mg per kg Clinical feature : Nausea , vomiting , abdominal discomfort

1.43k views • 17 slides

Funding sources :

Peginterferon Alfa-2a plus Ribavirin vs Peginterferon Alfa-2b plus Ribavirin for Chronic Hepatitis C Virus Infection in HIV-Infected Patients.

283 views • 17 slides

HISTORY

HISTORY. New Case File Registrations State-wise Distribution. Himachal Pradesh 10. Jammu & Kashmir 175. Haryana 70. Chandigarh 20. Uttaranchal 82. Punjab 89. Arunachal Pradesh 41. Delhi 94. Sikkim 10. Rajasthan 672. Nagaland 22. Uttar Pradesh 4630. Assam 720. Bihar

331 views • 16 slides

Background

Whitney Jones, PharmD Candidate 1 ; LeAnn B. Norris, PharmD, BCPS 2 ; P. Brandon Bookstaver, PharmD, BCPS 2 ; Richard Schulz, PhD 2 1 University of South Carolina College of Pharmacy, Columbia, SC; 2 South Carolina College of Pharmacy, USC Campus, Columbia, SC.

333 views • 12 slides

Q1:

Q1:. Drug A is a small and hydrophilic compound that distributes to extracellular fluids only. It has a volume of distribution of 5.6 L in a healthy 70-kg person . The free fraction of the drug in plasma is 0.1. What is the free fraction of the drug in the tissues?. fu = 0.1. V T = 13 L.

301 views • 9 slides