Supplementary Figure S1, Schneider et al. Fully migrated out of seeded (FM ratio). A. medium. WT sup. total PBMC. NS. KO sup. medium. NS. NS. NS. NS. WT sup. lymphocytes. NS. KO sup. medium. monocytes. WT sup. NS. KO sup. 0. 10. 20. 30. 40. 50. FM ratio (%).
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NK cells. Large granular lymphocytes ~5-15% human peripheral blood lymphocytes ~2-3% mouse spleen cells “non-specific” cytotoxicity standard targets K562 for human YAC-1 for mouse Cytokine production (IFN g, TNF a etc.)
T-Cells NK . Feb 13, 2006. T-cells. Antigens that are transported by dendritic cells to lymph nodes are recognized by naive T lymphocytes that recirculate through these lymph nodes.
T-Cells NK. Feb 13, 2006. T-cells. Antigens that are transported by dendritic cells to lymph nodes are recognized by naive T lymphocytes that recirculate through these lymph nodes.
CIS INTERACTION IN NK CELLS. Presented by Refael Cohen Project Advisor: Prof. Ramit Mehr Asya Kaplan Bar-Ilan University Faculty of Life Sciences Computational Biology 2009. INTRODUCTION: NK cell Immunological Synapse (NKIS). The receptors on NK cell:
NK cells Interferons J. Ochotná. NK cells. Part of antigen non-specific mechanisms (innate) They do not have antigen-specific receptors Recognize cells that have abnormally low MHCgpI expression (some tumor and virus infected cells)
NK cells Interferons J. Ochotná. NK cells. Part of antigen non-specific mechanisms (innate) They do not have antigen-specific receptors Recognize cells that have abnormally low MHCgpI expression (some tumor and virus infected cells)
NK cells Interferons J. Ochotná. NK cells. Part of antigen non-specific mechanisms (innate) They do not have antigen-specific receptors Recognize cells that have abnormally low MHCgpI (some tumor and virus infected cells)
NK Cells. T cells NK cells Activating and inhibitory receptors Immune evasion by viruses NK licensing NK cell memory NKT cells. Specialized lymphocytes. Immunity DeFranco. IG = 5x10 13 compared to αβ TCR = 10 18. γδ T cell function.
Functions of Th Cells, Th1 and Th2 Cells, Macrophages, Tc Cells, and NK Cells; Immunoregulation. Antigen-presenting cell. Ag. Ag. Tc cell. Ag. T h cell. Cytokines. B cell. APC. NK cell. Macrophage. Granulocyte. NK. Cytokines. Critical Role of Th Cells in Specific Immunity.
Supplementary Figure 1. Purified protein. Marker. Lig A 78kDa. Pkn1 70kDa. OmpA 35kDa. Supplementary Figure 1: Commassie staining of the SDS PAG showing purified protein fractions of LigA, Pkn1 and OmpA.