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Pathway Engineered Enzymatic de Novo Purine Nucleotide Synthesis

Pathway Engineered Enzymatic de Novo Purine Nucleotide Synthesis

Pathway Engineered Enzymatic de Novo Purine Nucleotide Synthesis. Heather L. Schultheisz, Blair R. Szymczyna, Lincoln G. Scott, and James R. Williamson. ACS Chem. Biol. , 2008 , 3 (8), 499-511. Outline. Enzymatic synthesis Importance of making isotopically labeled nucleotides

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610 views • 33 slides
Nucleotide Biosynthesis

Nucleotide Biosynthesis

Nucleotide Biosynthesis. nucleotides is essential for life processes. nucleotides are the activated precursors of nucleic acids. As such, they are necessary for the replication of the genome

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479 views • 29 slides
PRPP synthetase

PRPP synthetase

PRPP synthetase. Nucleoside phosphorylases. Phosphoribosyl transferases. The committed step of de novo purine nucleotide biosynthesis. Phosphoribosylamine synthase: cooperativity with respect to PRPP concentration & product inhibition. Outline of de novo purine nucleotide biosynthesis.

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387 views • 18 slides
NUCLEOTIDE BIOSYNTHESIS

NUCLEOTIDE BIOSYNTHESIS

NUCLEOTIDE BIOSYNTHESIS. N. N. O. C. C. C. C. P. P. P. ribose. nt biosynthesis. reduction rxns. NADPH. 1. Functions of Nucleotides Are Diverse. 1. 2. 3. in carbohydrate, lipid, protein, and nucleic acid synthesis. 4. 5. 6. Nucleotide Assembly. (source of carbons).

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393 views • 14 slides
NUCLEOTIDE BIOSYNTHESIS

NUCLEOTIDE BIOSYNTHESIS

NUCLEOTIDE BIOSYNTHESIS. N. N. O. C. C. C. C. P. P. P. ribose. nt biosynthesis. reduction rxns. NADPH. 1. Functions of Nucleotides Are Diverse. 1. 2. 3. in carbohydrate, lipid, protein, and nucleic acid synthesis. 4. 5. 6. Nucleotide Assembly. (source of carbons).

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261 views • 14 slides

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