'Motif model' presentation slideshows

Identifying co-regulation using Probabilistic Relational Models

Identifying co-regulation using Probabilistic Relational Models. by Christoforos Anagnostopoulos BA Mathematics, Cambridge University MSc Informatics, Edinburgh University. supervised by Dirk Husmeier. General Problematic. Promoter sequence data ...ACGTTAAGCCAT... ...GGCATGAATCCC.

851 views • 74 slides

Biological Motif Discovery

Biological Motif Discovery. Concepts Motif Modeling and Motif Information EM and Gibbs Sampling Comparative Motif Prediction Applications Transcription Factor Binding Site Prediction Epitope Prediction Lab Practical DNA Motif Discovery with MEME and AlignAce

864 views • 58 slides

Advanced Algorithms and Models for Computational Biology -- a machine learning approach

Advanced Algorithms and Models for Computational Biology -- a machine learning approach. Computational Genomics III: Motif Detection Eric Xing Lecture 6, February 6, 2005. Reading: Chap. 9, DTW book. Motifs - Sites - Signals - Domains.

703 views • 53 slides

Institute of Genetics and Selection of Industrial Microorganisms, Moscow, Russia

Combined network of transcription regulation and protein-protein interaction for inferring genome-wide functional linkages. Institute of Genetics and Selection of Industrial Microorganisms, Moscow, Russia. Russian-Indian Collaborating Project.

507 views • 44 slides

Sequence Logos

Sequence Logos. Height of each letter proportional to its frequency Height of all letters proportional to information content at that position. Probabilistic Motif: M ij ; 1 ? i ? W 1 ? j ? 4 M ij = Prob[ letter j, pos i ]

696 views • 44 slides

Developing computational methodologies

394 views • 39 slides

Motif Finding

Motif Finding. Regulation of Genes. Transcription Factor (Protein). RNA polymerase (Protein). DNA. Gene. Regulatory Element. Regulation of Genes. Transcription Factor (Protein). RNA polymerase. DNA. Regulatory Element. Gene. Regulation of Genes. New protein. RNA polymerase.

458 views • 34 slides

Motif Finding

Motif Finding. Regulation of Genes. Transcription Factor (Protein). RNA polymerase (Protein). DNA. Gene. Regulatory Element. Regulation of Genes. Transcription Factor (Protein). RNA polymerase. DNA. Regulatory Element. Gene. Regulation of Genes. New protein. RNA polymerase.

442 views • 34 slides

Gene Regulation and Microarrays

Gene Regulation and Microarrays. Finding Regulatory Motifs. Given a collection of genes with common expression, Find the TF-binding motif in common. Characteristics of Regulatory Motifs. Tiny Highly Variable ~Constant Size Because a constant-size transcription factor binds

392 views • 30 slides

Gene Regulation and Microarrays

Gene Regulation and Microarrays. Finding Regulatory Motifs. Given a collection of genes with common expression, Find the TF-binding motif in common. Characteristics of Regulatory Motifs. Tiny Highly Variable ~Constant Size Because a constant-size transcription factor binds

403 views • 30 slides

(Regulatory-) Motif Finding

307 views • 30 slides

Go over HW 4 Q/A on projects Q/A on guest lectures

276 views • 21 slides

The Gibbs Motif Sampler

The Gibbs Motif Sampler. By: Andrea Smith Introduction to Bioinformatics December 9 , 2004. Background:. Designed by Eric C. Rouchka and Bill Thompson Identifies motifs or conserved regions within sequences of DNA or protein. Used by several tools such as AlignACE. Background:.

309 views • 21 slides

The Gibbs Motif Sampler

The Gibbs Motif Sampler. By: Andrea Smith Introduction to Bioinformatics December 9 , 2004. Background:. Designed by Eric C. Rouchka and Bill Thompson Identifies motifs or conserved regions within sequences of DNA or protein. Used by several tools such as AlignACE. Background:.

297 views • 21 slides

Motif finding methods and algorithms

Motif finding methods and algorithms. Given a set of n promoters of n coregulated genes, find a motif common to the promoters. Both the PWM and the motif sequences are unknown. Common methods: 1 . Enumeration: Simplest case: look at the frequency of all n-mers

412 views • 17 slides