St. John’s Wort. Does it do anything?. Taxonomy. Kingdom Plantae Subkingdom Tracheobionta Superdivision Spermatophyta Division Magnoliophyta Class Magnoliopsida Subclass Dilleniidae Order Theales Family Clusiaceae Genus Hypericum L. Species Hypericum perforatum L.By owilson
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Antidepressant Drugs. What are Antidepressants?. Drugs that are used to relieve or prevent psychic depression.
Antidepressant Pharmacotherapy. Charles DeBattista, MD Stanford University. Outline. Phenomenology of MDD Risk Factors Co morbid conditions Economics Pathophysiology Monoamines Stress/Neurotrophic factors Classes of Agents SSRIs TCAs SNRIs MAOIs Other Agents
PHARMACOKINETICS. “What the body does to the drug”. Elimination. Pharmacokinetics (PK). The study of the disposition of a drug The disposition of a drug includes the processes of ADME A bsorption D istribution M etabolism E xcretion T oxicity. ADMET. DRUG R&D.
PHARMACOKINETICS. DR DINESH KURIAKOSE SABAH HOSPITAL. PHARMACOKINETICS. Quantitative and mathematical analysis of drug and drug metabolite level in the body Generally applied to the process of absorption, distribution, metabolism and excretion and to their description in numerical terms
Pharmacokinetics. Dr. M. Yulis Hamidy, MKes, MPdKed. Definition. Pharmacodynamics = the effects of the drug on the body Pharmacokinetics = the way the body affects the drug with time absorption distribution biotransformation / metabolism excretion of drugs. Passage of drugs through body.
PHARMACOKINETICS. WHAT THE BODY DOES TO THE DRUG. XENOBIOTIC. A compound to which the body is exposed that is foreign to the body. Includes drugs, industrial and environmental chemicals. Pharmacodynamics – concentration – effect Graded response Quantal response
Pharmacokinetics. Study of process of drug absorption, metabolism and excretion, distribution, biotransformation, excretion and half-life. Absorption. Process by which drug is made available for use in the body . Transfer drug from the body fluids to the tissue sites -. Absorption (Cont).
dr. Dian Nugrahenny, M.Biomed. Dr. drg. Nur Permatasari, MS. Laboratory of Pharmacology Faculty of Medicine Brawijaya University Email: email@example.com. PHARMACOKINETICS. PHARMACOKINETICS. Fate of drugs in the body A bsorption D istribution M etabolism/Biotransformation
Pharmacokinetics. Objective is to model the time course of the drug in plasma. One way to do this is through compartmental analysis . Compartments:
PHARMACOKINETICS. WHAT THE BODY DOES TO THE DRUG. XENOBIOTIC. A compound to which the body is exposed that is foreign to the body. Includes drugs, industrial and environmental chemicals. Pharmacodynamics â€“ concentration â€“ effect Graded response Quantal response